Tag: 164.2011

Multi-residue analysis of organic pollutants in hair and urine for matrices comparison was written by Hardy, Emilie M.;Duca, Radu C.;Salquebre, Guillaume;Appenzeller, Brice M. R.. And the article was included in Forensic Science International in 2015.Formula: C10H12O2 This article mentions the following:

Urine being currently the most classically used matrix for the assessment of human exposure to pesticides, a growing interest is yet observed in hair anal. for the detection of organic pollutants. The aim of the present work was to develop and to validate multi-residue anal. methods, as similar as possible, in order to determine pesticides and their metabolites in these two biol. matrixes despite their different nature. The list of parent compounds and their metabolites investigated here consisted of 56 compounds, including organochlorines, organophosphates, pyrethroids, carbamates, other pesticides and polychlorinated biphenyls (PCBs). Two different approaches were necessary for the anal. of non-polar compounds (mainly parents) on one hand and polar analytes (mainly metabolites) on the other hand. In the final procedure, extraction from hair was carried out with acetonitrile/water after sample decontamination and pulverization. Extract was split into two fractions, which were analyzed directly with solid phase microextraction (SPME) injection for non-polar compounds and after derivatization with liquid injection for polar compounds In urine, non-polar compounds were analyzed directly using SPME. Polar compounds were analyzed after acidic hydrolysis, liquid-liquid extraction with acetonitrile-cyclohexane-Et acetate, derivatization and liquid injection. Anal. was performed with gas chromatog. tandem mass spectrometry operating in neg. chem. ionization (GC-MS/MS-NCI) for all the compounds (non-polar and polar) in the two matrixes.In hair, limits of quantification (LOQ) ranged from 0.02 pg/mg for trifluralin to 5.5 pg/mg for diethylphosphate. In urine, LOQ ranged from 0.4 pg/mL for α-endosulfan to 4 ng/mL for dimethyldithiophosphate. The anal. of samples supplemented with standards and samples collected from an animal previously submitted to chronic exposure to pesticides confirmed that all the compounds were analyzable in both hair and urine. In addition, the levels of sensitivity reached with these methods were quite satisfactory with regard to previously published studies, and also considering the number of compounds investigated. In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Formula: C10H12O2).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Formula: C10H12O2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Biomarker Measurements of Concurrent Exposure to Multiple Environmental Chemicals and Chemical Classes in Children was written by Sexton, Ken;Ryan, Andrew D.;Adgate, John L.;Barr, Dana Boyd;Needham, Larry L.. And the article was included in Journal of Toxicology and Environmental Health, Part A: Current Issues in 2011.Computed Properties of C10H12O2 This article mentions the following:

Concern is mounting that children from disadvantaged, low-income neighborhoods are likely to be both more exposed to chem. hazards and more susceptible to related adverse health effects. This article reports measurements of >75 individual biomarkers spanning 7 chem./pollutant classes in blood and urine from more than 100 children living in a socioeconomically disadvantaged and ethnically diverse area of south Minneapolis, MN. Results indicate that a significant proportion of children in the study were at the high end of the exposure distribution compared to national reference ranges for a variety of environmental chems. and/or their metabolites, including phthalates, organochlorine pesticides, organophosphate pesticides, metals, polychlorinated biphenyls, and volatile organic compounds In addition, levels of cotinine in urine indicate that more than half the children were regularly exposed to environmental tobacco smoke, with the upper 10th percentile exposed to relatively high concentrations In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Computed Properties of C10H12O2).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Computed Properties of C10H12O2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Allelopathy of welsh onion root exudates on cucumber seed germination and Fusarium oxysporum f. sp. cucumerinum and GC-MS analysis was written by Xu, Ning;Wang, Chao;Wei, Min;Shi, Wei;Wang, Xiu-feng. And the article was included in Yuanyi Xuebao in 2012.HPLC of Formula: 1563-38-8 This article mentions the following:

The allelopathy of welsh onion root exudates collected by continuous root exudates trapping system (CRETS) was studied on cucumber seed germination and Fusarium oxysporum f. sp. cucumerinum, and the components of the root exudates were identified by gas chromatog.-mass spectrometry (GS-MS). The results showed that the seed germination and sprout growth of cucumber were promoted by root exudates of welsh onion at low concentration while suppressed at high concentration, the allelopathy of ‘Yuanzang’ was stronger than ‘Zhangqiu’. Inhibitory effects on hypha growth and spore germination of Fusarium oxysporum f. sp. cucumerinum enhanced with increasing concentration of root exudates, and ‘Yuanzang’ showed stronger effects than ‘Zhangqiu’. Heterocyclic, ester, amide, acid, hydrocarbon, aldehyde, ketone, phenol, alc., ether, naphthalene compounds were detected in root exudates of Welsh onion, of which heterocyclic, ester and amide were the most compounds Phthalate esters and benzothiazole derivatives had greater relative contents while p-cresol 2,2′-methylenebis 6-tert-butyl-, benzyl benzoate, benzoic acid p-tolyl ester, 2-(methylthio) Ph isothiocyanate had lower relative contents, which were higher in ‘Yuanzang’ than in ‘Zhangqiu’. In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8HPLC of Formula: 1563-38-8).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. They are also prone to polymerisation in the presence of concentrated mineral acids and Lewis acids.HPLC of Formula: 1563-38-8

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Practical aspects in gas chromatography-mass spectrometry for the analysis of pesticide residues in exotic fruits was written by Espana Amortegui, Julio Cesar;Guerrero Dallos, Jairo Arturo. And the article was included in Food Chemistry in 2015.Synthetic Route of C10H12O2 This article mentions the following:

The most relevant parameters of a multimode inlet were optimized to increase the injection volume up to 25 μL using solvent vent mode in order to improve the sensitivity of the gas chromatog.-mass spectrometry system. Consequently, the implementation of a concurrent backflushing was necessary to largely prevent the expected loss of performance derived from such matrix load out of a general-purpose extraction (EN-15622-QuEChERS). Addnl., four mixtures of compounds used as analyte protectants were tested using spiked physalis to enhance the quality of signals. The chosen mixture remarkably improved sensitivity and yield better peak shapes, significantly more than others also tested. The anal. of pesticide residues in exotic fruits using instruments of limited selectivity is challenging since these complex matrixes usually give notably dirty extracts This scheme included an instrumental optimization and the addition of selected compounds that enabled to selectively reach limits of quantitation of 0.01 mg kg^-1 for most analytes. In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Synthetic Route of C10H12O2).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Synthetic Route of C10H12O2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Cloud point extraction coupled with derivative of carbofuran as a preconcentration step prior to HPLC was written by Chen, Jian-bo;Zhao, Wei-jun;Liu, Wei;Zhou, Zhi-ming;Yang, Ming-min. And the article was included in Food Chemistry in 2009.Name: 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol This article mentions the following:

Carbofuran can be hydrolyzed to from 2,3-dihydro-2,2-dimethyl-7-benzofuranol (BF). BF is coupled with 4-aminoantipyrine (AP) in presence of potassium ferricyanide (K₃Fe(CN)₆) to generate red colored derivative(BFAP)having λmax 530 nm. Cloud point extraction (CPE) methodol. and using surfactant Triton X-100 as extractant was applied as a preconcentration step prior to HPLC, the surfactant-rich phase containing BFAP was then analyzed by HPLC in visible region. The high back ground absorbance of Triton X-100 in UV region was completely avoided. A new visible detection method with high-performance liquid chromatog. (HPLC) has been developed for the determination of carbofuran. Using this method, we found that carbofuran residues could be determined with recoveries ranging from 80.4% to 84.5%, relative standard deviations in the range of 2.51-3.26% for three fortified rice levels, and the limit of detection as 5.0 × 10^-4 cJ/cK. In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Name: 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Name: 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Comparison of solid phase- and liquid/liquid-extraction for the purification of hair extract prior to multi-class pesticides analysis was written by Duca, Radu-Corneliu;Salquebre, Guillaume;Hardy, Emilie;Appenzeller, Brice M. R.. And the article was included in Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences in 2014.Computed Properties of C10H12O2 This article mentions the following:

The present study focuses on the influence of a purification step – after extraction of pesticides from hair and before anal. of the extract – on the sensitivity of anal. methods including compounds from different chem. classes (both parent and metabolites). Sixty-seven pesticides and metabolites from different chem. classes were tested here: organochlorines, organophosphates, carbamates, pyrethroids, ureas, azoles, phenylpyrazoles and neonicotinoids. Two gas chromatog.-neg. chem. ionization-tandem mass spectrometry methods and one based on ultra-performance liquid chromatog.-electrospray tandem mass spectrometry were used. Seven solid-phase extraction cartridges: C18, S-DVB, PS-DVB, GCB, GCB/PSA, SAX/PSA and Florisil/PSA were tested and compared to more classical liquid-liquid extraction procedures using Et acetate, hexane and dichloromethane. Although LLE allowed obtaining good results for some compounds, on the whole, SPE clearly provided better recovery for the majority of the pesticide residues tested in the present study. GCB/PSA was clearly the best suited to nonpolar compounds such as organochlorines, pyrethroids and organophosphates, with recovery ranging from 45.9% (diflufenican) to 117.1% (parathion methyl). For hydrophilic metabolites (e.g. dialkyl phosphates and other organophosphate metabolites, pyrethroid metabolites, phenols and carbamate metabolites), the best results were obtained with PS-DVB, with recovery ranged from 10.3% (malathion monocarboxylic acid) to 93.1% (p-nitrophenol). For hydrophilic parent pesticides (e.g. neonicotinoids, carbamates, azoles) and metabolites without nucleophilic functions, the best recovery was obtained with SAX/PSA, with recovery ranging from 52.1% (3-hydroxycarbofuran) to 100.9% (3,4-dichloroaniline). Solid phase extraction was found to be more suitable than the liquid-liquid extraction for pesticides and their metabolites determination in terms of number of extracted compounds and their recovery. Moreover, the use of solid phase extraction cartridges has enabled the reduction of the anal. background noise, resulting in better chromatog. separations In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Computed Properties of C10H12O2).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran derivatives have shown many biological activities, including antifungal and antimicrobial properties, and acting as antagonists of H3 receptors and angiotensin II. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Computed Properties of C10H12O2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

2-(2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yloxy)acetic acid monohydrate was written by Yang, Lin-Tao;Ye, Jiao;Luo, Xian-Fu;Hu, Ai-Xi. And the article was included in Acta Crystallographica, Section E: Structure Reports Online in 2010.Computed Properties of C10H12O2 This article mentions the following:

In the title compound, C₁₂H₁₄O₄·H₂O, the dihydrobenzofuran ring adopts an envelope conformation with the substituted C atom 0.142 (1) Å out of the least-squares plane. In the crystal, the components are linked via intermol. O_water-H…O and O-H…O_water hydrogen-bonding interactions, forming a three-dimensional network. Crystallog. data are given. In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Computed Properties of C10H12O2).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Computed Properties of C10H12O2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Practical aspects in gas chromatography-mass spectrometry for the analysis of pesticide residues in exotic fruits was written by Espana Amortegui, Julio Cesar;Guerrero Dallos, Jairo Arturo. And the article was included in Food Chemistry in 2015.Synthetic Route of C10H12O2 This article mentions the following:

The most relevant parameters of a multimode inlet were optimized to increase the injection volume up to 25 μL using solvent vent mode in order to improve the sensitivity of the gas chromatog.-mass spectrometry system. Consequently, the implementation of a concurrent backflushing was necessary to largely prevent the expected loss of performance derived from such matrix load out of a general-purpose extraction (EN-15622-QuEChERS). Addnl., four mixtures of compounds used as analyte protectants were tested using spiked physalis to enhance the quality of signals. The chosen mixture remarkably improved sensitivity and yield better peak shapes, significantly more than others also tested. The anal. of pesticide residues in exotic fruits using instruments of limited selectivity is challenging since these complex matrixes usually give notably dirty extracts This scheme included an instrumental optimization and the addition of selected compounds that enabled to selectively reach limits of quantitation of 0.01 mg kg^-1 for most analytes. In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Synthetic Route of C10H12O2).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Synthetic Route of C10H12O2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

Cloud point extraction coupled with derivative of carbofuran as a preconcentration step prior to HPLC was written by Chen, Jian-bo;Zhao, Wei-jun;Liu, Wei;Zhou, Zhi-ming;Yang, Ming-min. And the article was included in Food Chemistry in 2009.Name: 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol This article mentions the following:

Carbofuran can be hydrolyzed to from 2,3-dihydro-2,2-dimethyl-7-benzofuranol (BF). BF is coupled with 4-aminoantipyrine (AP) in presence of potassium ferricyanide (K₃Fe(CN)₆) to generate red colored derivative(BFAP)having λmax 530 nm. Cloud point extraction (CPE) methodol. and using surfactant Triton X-100 as extractant was applied as a preconcentration step prior to HPLC, the surfactant-rich phase containing BFAP was then analyzed by HPLC in visible region. The high back ground absorbance of Triton X-100 in UV region was completely avoided. A new visible detection method with high-performance liquid chromatog. (HPLC) has been developed for the determination of carbofuran. Using this method, we found that carbofuran residues could be determined with recoveries ranging from 80.4% to 84.5%, relative standard deviations in the range of 2.51-3.26% for three fortified rice levels, and the limit of detection as 5.0 × 10^-4 cJ/cK. In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Name: 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Name: 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem

2-(2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yloxy)acetic acid monohydrate was written by Yang, Lin-Tao;Ye, Jiao;Luo, Xian-Fu;Hu, Ai-Xi. And the article was included in Acta Crystallographica, Section E: Structure Reports Online in 2010.Computed Properties of C10H12O2 This article mentions the following:

In the title compound, C₁₂H₁₄O₄·H₂O, the dihydrobenzofuran ring adopts an envelope conformation with the substituted C atom 0.142 (1) Å out of the least-squares plane. In the crystal, the components are linked via intermol. O_water-H…O and O-H…O_water hydrogen-bonding interactions, forming a three-dimensional network. Crystallog. data are given. In the experiment, the researchers used many compounds, for example, 2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8Computed Properties of C10H12O2).

2,2-Dimethyl-2,3-dihydrobenzofuran-7-ol (cas: 1563-38-8) belongs to benzofurans derivatives. Benzofuran is the “”parent”” of many related compounds with more complex structures. For example, psoralen is a benzofuran derivative that occurs in several plants. In nature, benzofurans have occupied an important role among the plant phenols & several pharmacologically active compounds.Computed Properties of C10H12O2

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem