Kinetics of bromination of benzofurans by phenyltrimethylammonium tribromide was written by Suryawanshi, V. S.. And the article was included in Journal of Chemical and Pharmaceutical Research in 2017.Formula: C10H7BrO2 This article mentions the following:
The kinetics of the reaction between different 2-acetyl benzofuran (BF) and phenyltrimethylammonium tribromide (PTT) has been studied spectrophotometrically in acetic acid under varying conditions. The results indicate first order kinetic with respect to 2-acetyl benzofurans (BF) and inverse first order due to phenyltrimethylammonium tribromide (PTT). Effect of ionic strength and dielec. constant on reaction rate was observed The rates of reaction are measured at different temperature and activation parameters have been calculated The products of the bromination are the corresponding 2-bromoacetyl benzofurans. In the experiment, the researchers used many compounds, for example, 1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6Formula: C10H7BrO2).
1-(5-Bromobenzofuran-2-yl)ethanone (cas: 38220-75-6) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. Introduction of benzofurans in organic synthesis, particularly drug synthesis, involves generally the use of their metalated species as nucleophiles in addition reactions or in metal-catalysed cross-coupling reactions.Formula: C10H7BrO2
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem