So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Garcia-Urdiales, Eduardo; Rebolledo, Francisca; Gotor, Vicente researched the compound: (R)-Ethyl 4-chloro-3-hydroxybutanoate( cas:90866-33-4 ).Name: (R)-Ethyl 4-chloro-3-hydroxybutanoate.They published the article 《Enzymatic ammonolysis of ethyl (±)-4-chloro-3-hydroxybutanoate. Chemoenzymatic syntheses of both enantiomers of pyrrolidin-3-ol and 5-(chloromethyl)-1,3-oxazolidin-2-one》 about this compound( cas:90866-33-4 ) in Tetrahedron: Asymmetry. Keywords: enzymic ammonolysis ethyl chlorohydroxybutanoate; chemoenzymic preparation pyrrolidinol chloromethyloxazolidinone enantiomer; lipase B catalysis ammonolysis kinetic resolution. We’ll tell you more about this compound (cas:90866-33-4).
Lipase B from Candida antarctica efficiently catalyzed the kinetic resolution of Et (±)-4-chloro-3-hydroxybutanoate through an ammonolysis reaction. With this methodol., both enantiomers of 4-chloro-3-hydroxybutanamide were prepared and converted into pyrrolidin-3-ol and 5-(chloromethyl)-1,3-oxazolidin-2-one by simple processes consisting of a reduction reaction and a Hofmann rearrangement, resp.
In addition to the literature in the link below, there is a lot of literature about this compound((R)-Ethyl 4-chloro-3-hydroxybutanoate)Name: (R)-Ethyl 4-chloro-3-hydroxybutanoate, illustrating the importance and wide applicability of this compound(90866-33-4).
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem