Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Product Details of 174775-48-5, 174775-48-5, Name is Ethyl 5-aminobenzofuran-2-carboxylate, SMILES is O=C(C1=CC2=CC(N)=CC=C2O1)OCC, belongs to benzofurans compound. In a document, author is Assiri, Mohammed M., introduce the new discover.
Some novel substituted benzofurans and annulated furochromenes were obtained through the treatment of the novel (2E)-3-(4,9-dimethoxy-5-oxo-5H-furo[3,2-g]chromen-6-yl)acrylonitrile (2) by some active carbon nucleophiles such as active methylene ketones and methylene nitriles. Thus, the reaction of acrylonitrile 2 with acetylacetone, ethyl acetoacetate, diethylmalonate, and acetoacetanilide in ethanol containing piperidine produced efficiently the corresponding polyfunctionalized benzonitrile derivatives 3?5 and furochromeno-pyridine 6, respectively. Also, treatment of acrylonitrile 2 with some methylene nitriles such as malononitrile, ethyl cyanoacetate, and malononitrile dimer afforded the annulated furochromene derivatives 7?9. Furthermore, the pyrido[1,2-a] benzimidazole system 10 was furnished via reaction of acrylonitrile 2 with 2-(1?H-benzimidazol-2-yl)acetonitrile. These reactions took place through Michael addition, retro-Michael, and ?-pyrone ring opening followed by different types of recyclization. The chemical structures of the novel products were established on the basis of their spectral data and elemental analysis.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 174775-48-5. Product Details of 174775-48-5.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem