Ota, Tomomi published the artcileSelective preparation and cyclization of 2-(2-hydroxyphenyl)-2-(isopropylthio)ethanols. New Synthesis of 1-benzofurans, Product Details of C10H10O2, the main research area is benzofuran; acetoxyisopropylthioethylphenol regioselective preparation cyclization; phenol alkylation isopropylthioethyl acetate.
Reaction of 2,4-R(R1)C6H3OH (R = H, R1 = H, Ph, Me, MeO, Cl, cyclohexyl, etc.; R = Me, MeO, Cl, R1 = H) with Me2CHSCH2CH2OMe activated by SO2Cl2 afforded 2-[2-acetoxy-1-(isopropylthio)ethyl]phenols I (R, R1 = as above) regioselectively, via [2,3]sigmatropic rearrangement of phenoxysulfonium ylides. The ortho-alkylated phenols thus obtained were cyclized with concentrate HCl in MeOCH2CH2OH to 1-benzofuran II (R, R1 = as above). 2-Methyl- and 2-phenyl-1-benzofuran were prepared similarly.
Journal of the Chemical Society, Perkin Transactions 3: Organic and Bio-Organic Chemistry published new progress about Alkylation. 13391-27-0 belongs to class benzofurans, name is 5-Methoxy-2-methylbenzofuran, and the molecular formula is C10H10O2, Product Details of C10H10O2.
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem