Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 66357-35-5, Name is Ranitidine, SMILES is O=[N+]([O-])/C=C(NCCSCC1=CC=C(O1)CN(C)C)NC, in an article , author is Bos, Maxence, once mentioned of 66357-35-5, Quality Control of Ranitidine.
Organocatalytic Gram-Scale Synthesis and Alkylation of Heteroaryl and Electron-Rich Aryl alpha-Substituted gamma-Lactones
The synthesis of gamma-lactones alpha-substituted with heterocycles and electron-rich aromatic rings is described. The method, based on a sequence involving an organocatalytic addition of boronic acid to the 5-hydroxyfuran-2(5H)-one, followed by reduction and lactonization, gives access to broad range of gamma-lactones on a gram scale. Among these, gamma-lactones bearing a benzofuran, a benzothiophene, and an indole ring were alkylated in mild catalytic conditions to construct alpha-quaternary stereocenters. Interesting mild oxidation reaction, using molecular oxygen, was also highlighted during this study.
But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 66357-35-5, you can contact me at any time and look forward to more communication. Quality Control of Ranitidine.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem