New downstream synthetic route of 90866-33-4

Compounds in my other articles are similar to this one((R)-Ethyl 4-chloro-3-hydroxybutanoate)Recommanded Product: (R)-Ethyl 4-chloro-3-hydroxybutanoate, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic.Wong, Chihuey; Drueckhammer, Dale G.; Sweers, Henri M. researched the compound: (R)-Ethyl 4-chloro-3-hydroxybutanoate( cas:90866-33-4 ).Recommanded Product: (R)-Ethyl 4-chloro-3-hydroxybutanoate.They published the article 《Enzymic vs. fermentative synthesis: thermostable glucose dehydrogenase catalyzed regeneration of NAD(P)H for use in enzymic synthesis》 about this compound( cas:90866-33-4 ) in Journal of the American Chemical Society. Keywords: immobilized glucose dehydrogenase thermostability Bacillus; enzymic organic synthesis NADH NADPH regeneration. We’ll tell you more about this compound (cas:90866-33-4).

Procedures are described for regeneration of reduced nicotinamide cofactors, NADH and NADPH, from NAD(P) based on glucose and thermostable glucose dehydrogenase from Bacillus cereus immobilized in polyacrylamide gels. The turnover number for NAD in a synthesis of 200 mmol of D-lactate was 40,000. Application of this system to other syntheses was demonstrated with preparations of Et (R)-4-chloro-3-hydroxybutanoate, (R)-2,2,2-trifluoro-1-phenylethanol, Et (S)-3-hydroxyvalerate, (S)-lactaldehyde di-Me acetal, and (S)-3-hydroxybutanal di-Me acetal. Further investigation of the kinetics regarding the thermoresistance of glucose dehydrogenase in the presence of NaCl was carried out, and it appeared that the enhancement by NaCl of the thermal stability of the enzyme was approx. 3rd-order. The immobilized glucose dehydrogenase incubated at 55°, pH 7.5, for 7 days was still fully active, whereas many other enzymes are completely inactivated in 1-2 days. Addition of NaCl enhanced the thermal stability more significantly than the immobilization did, and a marked increase in thermal stability was observed with these 2 combined factors. The half-life of the immobilized glucose dehydrogenase at 55° in a buffer (pH 7.0-7.5) containing 1M NaCl was >30 days compared to 3 min for the free enzyme, corresponding to an overall ∼50,000-fold increase in thermal stability.

Compounds in my other articles are similar to this one((R)-Ethyl 4-chloro-3-hydroxybutanoate)Recommanded Product: (R)-Ethyl 4-chloro-3-hydroxybutanoate, you can compare them to see their pros and cons in some ways,such as convenient, effective and so on.

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem