Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Journal of Biotechnology called Effective biosynthesis of ethyl (R)-4-chloro-3-hydroxybutanoate by supplementation of L-glutamine, D-xylose and β-cyclodextrin in n-butyl acetate-water media, Author is He, Yu-Cai; Tao, Zhi-Cheng; Ding, Yun; Zhang, Dan-Ping; Wu, Yin-Qin; Lu, Yun; Liu, Feng; Xue, Yu-Feng; Wang, Cheng; Xu, Jian-He, which mentions a compound: 90866-33-4, SMILESS is O=C(OCC)C[C@@H](O)CCl, Molecular C6H11ClO3, Application of 90866-33-4.
To avoid adding NAD+ and effectively transform Et 4-chloro-3-oxobutanoate, the mixture of L-glutamine (200 mM) and D-xylose (250 mM) was added into in Bu acetate-water (10:90, volume/volume) biphasic system instead of NAD+ for increasing the biocatalytic efficiency. To further improve the synthesis of optically pure Et (R)-4-chloro-3-hydroxybutanoate (>99% ee), β-cyclodextrin was also added into this reaction media, and Et (R)-4-chloro-3-hydroxybutanoate (>99% ee) could be effectively synthesized from 800 mM Et 4-chloro-3-oxobutanoate in the yield of 100% by whole-cells of recombinant Escherichia coli CCZU-A13. Finally, the possible mechanism for improving the reductase activity by supplementation of L-glutamine, D-xylose and β-CD was proposed. In conclusion, this strategy has high potential for the effective biosynthesis of Et (R)-4-chloro-3-hydroxybutanoate (>99% ee).
From this literature《Effective biosynthesis of ethyl (R)-4-chloro-3-hydroxybutanoate by supplementation of L-glutamine, D-xylose and β-cyclodextrin in n-butyl acetate-water media》,we know some information about this compound(90866-33-4)Application of 90866-33-4, but this is not all information, there are many literatures related to this compound(90866-33-4).
Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem