Mazza, Mariarosa et al. published their research in ACS Nano in 2013 | CAS: 200115-86-2

H-Arg(Pbf)-OH (cas: 200115-86-2) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Recommanded Product: H-Arg(Pbf)-OH

Nanofiber-Based Delivery of Therapeutic Peptides to the Brain was written by Mazza, Mariarosa;Notman, Rebecca;Anwar, Jamshed;Rodger, Alison;Hicks, Matthew;Parkinson, Gary;McCarthy, Dave;Daviter, Tina;Moger, Julian;Garrett, Natalie;Mead, Tania;Briggs, Michael;Schatzlein, Andreas G.;Uchegbu, Ijeoma F.. And the article was included in ACS Nano in 2013.Recommanded Product: H-Arg(Pbf)-OH This article mentions the following:

The delivery of therapeutic peptides and proteins to the central nervous system is the biggest challenge when developing effective neuropharmaceuticals. The central issue is that the blood-brain barrier is impermeable to most mols. Here we demonstrate the concept of employing an amphiphilic derivative of a peptide to deliver the peptide into the brain. The key to success is that the amphiphilic peptide should by design self-assemble into nanofibers wherein the active peptide epitope is tightly wrapped around the nanofiber core. The nanofiber form appears to protect the amphiphilic peptide from degradation while in the plasma, and the amphiphilic nature of the peptide promotes its transport across the blood-brain barrier. Therapeutic brain levels of the amphiphilic peptide are achieved with this strategy, compared with the absence of detectable peptide in the brain and the consequent lack of a therapeutic response when the underivatized peptide is administered. In the experiment, the researchers used many compounds, for example, H-Arg(Pbf)-OH (cas: 200115-86-2Recommanded Product: H-Arg(Pbf)-OH).

H-Arg(Pbf)-OH (cas: 200115-86-2) belongs to benzofurans derivatives. Many natural or synthetic compounds containing benzofuran skeletons have been found to possess remarkable activity as agrochemicals and pharmaceuticals. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Recommanded Product: H-Arg(Pbf)-OH

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem