HPLC of Formula: 53860-74-5On October 7, 2008 ,《New scaffolds for the design of selective estrogen receptor modulators》 was published in Organic & Biomolecular Chemistry. The article was written by Martin-Santamaria, Sonsoles; Rodriguez, Jose-Juan; de Pascual-Teresa, Sonia; Gordon, Sandra; Bengtsson, Martin; Garrido-Laguna, Ignacio; Rubio-Viqueira, Belen; Lopez-Casas, Pedro P.; Hidalgo, Manuel; de Pascual-Teresa, Beatriz; Ramos, Ana. The article contains the following contents:
In the present work we report the synthesis of four new ER ligands which can be used as scaffolds for the introduction of the basic side chains necessary for antiestrogenic activity. Affinities and agonist/antagonist characterization of the ligands for both ERα and ERβ have been determined in a competitive radioligand assay, and in an in vitro coactivator recruitment functional assay, resp. Mol. modeling techniques have been used in order to rationalize the exptl. results. Compound 2 is reported as a novel ERβ-agonist/ERα-antagonist. Two compounds show an interesting antitumor profile towards two pancreatic cancer cell lines and have been selected for in vivo assays. In addition to this study using 6-Methoxybenzofuran-2-carbaldehyde, there are many other studies that have used 6-Methoxybenzofuran-2-carbaldehyde(cas: 53860-74-5HPLC of Formula: 53860-74-5) was used in this study.
6-Methoxybenzofuran-2-carbaldehyde(cas: 53860-74-5) belongs to benzofurans.HPLC of Formula: 53860-74-5Benzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem