《Synthesis of 2-amino-4-(2-benzofuryl)-Δ1-pyrrolines and study of their antiarrhythmic properties》 was written by Maillard, Jacques; Langlois, Michel; Tri, Vo Van; Guillonneau, Claude; Legeai, Jacques; Benharkate, Marguerite; Blozovski, Mladen. Quality Control of 6-Methoxybenzofuran-2-carbaldehyde And the article was included in European Journal of Medicinal Chemistry on August 31 ,1983. The article conveys some information:
2-Ethoxy-1-pyrrolines I (R = furyl, thienyl, benzofuryl, benzothienyl) were converted to amino analogs II (R1 = H, alkyl; R2 = H, alkyl, allyl, propargyl, CH2CH2OH, CH2CH2NMe2, phenethyl, Ph, OMe, OCH2Ph; or NR1R2 = pyrrolidino, morpholino, 4-methyl-1-piperazinyl), which showed antiarrhythmic activity. I (R = 2-benzofuryl) was heated with Me2NH.HCl in EtOH to give II (R = 2-benzofuryl, R1 = R2 = Me) hydrochloride. The results came from multiple reactions, including the reaction of 6-Methoxybenzofuran-2-carbaldehyde(cas: 53860-74-5Quality Control of 6-Methoxybenzofuran-2-carbaldehyde)
6-Methoxybenzofuran-2-carbaldehyde(cas: 53860-74-5) belongs to benzofurans.Quality Control of 6-Methoxybenzofuran-2-carbaldehydeBenzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem