Liu, Yong; Xing, Shuya; Zhang, Jing; Liu, Wen; Xu, Yuenian; Zhang, Yan; Yang, Kefang; Yang, Lei; Jiang, Kezhi; Shao, Xinxin published an article in 2022, the title of the article was Construction of diverse C-S/C-Se bonds via nickel catalyzed reductive coupling employing thiosulfonates and a selenosulfonate under mild conditions.Formula: C8H5IO And the article contains the following content:
A nickel-catalyzed reductive cross coupling between organic iodides and thiosulfonates and a selenosulfonate under mild conditions was disclosed. This practical method provides a facile access to a series of unsym. thioethers with low catalyst loading, good functional group tolerance, and excellent chemo-selectivity. Notably, the synthetic applications of the approach feature scaling-up of reactions, late-stage modification of pharmaceuticals, and preparation of various useful targeted compounds, including sulfoximine, bipyridine, and vortioxetine. Primary mechanistic studies showed that a radical pathway was involved. Moreover, diverse C-S/C-Se bond formations were achieved under mild reaction conditions. The experimental process involved the reaction of 5-Iodobenzofuran(cas: 60770-67-4).Formula: C8H5IO
The Article related to organic iodide thiosulfonate nickel catalyst chemoselective reductive coupling, thioether preparation, selenosulfonate organic iodide nickel catalyst chemoselective reductive coupling, selenoether preparation and other aspects.Formula: C8H5IO
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem