Li, Junxuan; Zhou, Jinlei; Wang, Yumei; Yu, Yue; Liu, Qiang; Yang, Tilong; Chen, Huoji; Cao, Hua published the artcile< Mechanistic insight into the synergistic Cu/Pd-catalyzed carbonylation of aryl iodides using alcohols and dioxygen as the carbonyl source>, Category: benzofurans, the main research area is aryl iodide alc carbonylation dioxygen carbonyl source mechanistic insight.
Pd-catalyzed carbonylation, as an efficient synthetic approach for the installation of carbonyl groups in organic compounds, has been one of the most important research fields in the past decade. Although elegant reactions that allow highly selective carbonylations have been developed, straightforward routes with improved reaction activity and broader substrate scope remain long-term challenges for new practical applications. Here, authors show a new type of synergistic Cu/Pd-catalyzed carbonylation reaction using alcs. and dioxgen as the carbonyl sources. A broad range of aryl iodides and alcs. are compatible with this protocol. The reaction is concise and practical due to the ready availability of the starting materials and the scalability of the reaction. In addition, the reaction affords lactones and lactams in an intermol. fashion. Moreover, DFT calculations have been performed to study the detailed mechanisms.
Science China: Chemistrypublished new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 531-88-4 belongs to class benzofurans, and the molecular formula is C10H10O4, Category: benzofurans.
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem