Lee, Yu-Jin published the artcileIsolation and identification of antioxidant polyphenolic compounds in mulberry (Morus alba L.) seeds, Category: benzofurans, the publication is Han’guk Sikp’um Yongyang Kwahak Hoechi (2011), 40(4), 517-524, database is CAplus.
Eleven polyphenolic compounds, including procatechuic and chlorogenic acids, (+)-dihydroquercetin, rutin, isoquercitrin, quercitrin, (+)-dihydrokaempferol, trans-resveratrol, moracin, quercetin and 4-prenylmoracin were isolated and purified from the methanolic extract of defatted mulberry seed residue by a series of column chromatog. including silica gel, Sephadex LH-20, and ODS-A, and their chem. structures were identified by spectral anal. The antioxidant activities of the eleven isolated polyphenolic compounds were measured spectrophotometrically using DPPH radical. Among the eleven polyphenolic compounds tested, rutin (IC50=20.2 μM), isoquercitrin (IC50=22.5 μM), quercitrin (IC50=24.6 μM), quercetin (IC50=27.8 μM), (+)-dihydroquercetin (IC50=28.9 μM), and chlorogenic acid (IC50=30.6 μM) exhibited stronger antioxidant activity than L-ascorbic acid (IC50=31.5 μM) and α-tocopherol (IC50=52.3 μM), whereas procatechuic acid (IC50=68.2 μM) showed lower activity. In addition, (+)-dihydrokaempferol (IC50=33.8 μM), trans-resveratrol (IC50=36.2 μM), moracin (IC50=47.6 μM), and 4-prenylmoracin (IC50=48.2 μM) exhibited moderate antioxidant activity. Furthermore, levels of the eleven polyphenolic compounds from three different types of mulberry seeds were quantified by HPLC, and their contents were as follows: rutin (31.1-60.0 mg/100 g)> quercitrin (7.2-34.2 mg/100 g)> (+)-dihydroquercetin (13.2-33.1 mg/100 g)> quercetin (15.8-19.5 mg/100 g)> 4-prenylmoracin (10.5-43.3 mg/100 g)> isoquercitrin (5.8-15.4 mg/100 g)> chlorogenic acid (0.0-15.3 mg/100 g)> moracin (4.7-7.2 mg/100 g)> procatechuic acid (0.0-11.6 mg/100 g)> (+)-dihydrokaempferol and trans-resveratrol (<0.1 mg/100 g). The ‘Daesungppong’ mulberry seeds among the three cultivars had higher flavonoid contents, such as rutin and quercetin derivatives, while the ‘Iksuppong’ seeds had the highest contents of phenolic acids and moracin derivatives ‘Cheongilppong’ had lower amounts of polyphenolic compounds than the other two mulberry seeds. These results indicate that mulberry seeds containing antioxidant polyphenolic compounds may be potentially useful sources of anti-diabetic, anti-hypertensive, and anti-aging agents for functional foods and cosmetics.
Han’guk Sikp’um Yongyang Kwahak Hoechi published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Category: benzofurans.
Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem