Design and synthesis of fluorescent SGLT2 inhibitors was written by Lansdell, Mark I.;Burring, Denise J.;Hepworth, David;Strawbridge, Matthew;Graham, Emily;Guyot, Thierry;Betson, Mark S.;Hart, James D.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2008.Product Details of 92557-80-7 This article mentions the following:
The design and synthesis of the first fluorophore-conjugated SGLT2 inhibitors is described. The mode of linking the fluorophore to the SGLT2 pharmacophore was crucial in achieving optimum potency. Superior potency to phlorizin was provided by examples containing TAMRA, BODIPY, Cy3B and NBD fluorophores. In the experiment, the researchers used many compounds, for example, 2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate (cas: 92557-80-7Product Details of 92557-80-7).
2,5-Dioxopyrrolidin-1-yl 3′,6′-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9′-xanthene]-5-carboxylate (cas: 92557-80-7) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Product Details of 92557-80-7
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem