Haraguchi, Ryosuke’s team published research in Organic Letters in 19 | CAS: 69626-75-1

Organic Letters published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Safety of 2-Iodobenzofuran.

Haraguchi, Ryosuke published the artcilePalladium-Catalyzed Formylation of Arylzinc Reagents with S-Phenyl Thioformate, Safety of 2-Iodobenzofuran, the publication is Organic Letters (2017), 19(7), 1646-1649, database is CAplus and MEDLINE.

In the presence of Pd(OAc)2 and tri(2-furyl)phosphine in toluene/THF, arylzinc reagents derived from aryl iodides and an alkenylzinc reagent were chemoselectively formylated with S-Ph thioformate PhSCHO to yield aryl aldehydes ArCHO (Ar = 4-NCC6H4, 4-EtO2CC6H4, 4-i-Pr2NCOC6H4, 4-ClC6H4, 4-BrC6H4, 3-ClC6H4, 3-BrC6H4, 4-MeOC6H4, 1,3-benzodioxol-5-yl, 4-HOC6H4, 4-Me2NC6H4, 2-MeC6H4, 2-MeOC6H4, 2,4,6-Me3C6H2, 2-naphthyl, 1-naphthyl, 2-thienyl, 2-benzofuranyl, 1-Me-5-indolyl) and trans-cinnamaldehyde in 56-97% yields. Using deuterated and 13C-labeled deuterated and 13C-labeled S-Ph thioformate, 4-DCOC6H4CN and 4-BrC6H413CH:CH2 were prepared in high isotopic purities by this method.

Organic Letters published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Safety of 2-Iodobenzofuran.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem