Fun Route: New Discovery of 90866-33-4

If you want to learn more about this compound((R)-Ethyl 4-chloro-3-hydroxybutanoate)HPLC of Formula: 90866-33-4, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(90866-33-4).

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: (R)-Ethyl 4-chloro-3-hydroxybutanoate(SMILESS: O=C(OCC)C[C@@H](O)CCl,cas:90866-33-4) is researched.Recommanded Product: Ethyl 2-(2-oxopyrrolidin-1-yl)acetate. The article 《Efficient synthesis of optically pure alcohols by asymmetric hydrogen-transfer biocatalysis: application of engineered enzymes in a 2-propanol-water medium》 in relation to this compound, is published in Applied Microbiology and Biotechnology. Let’s take a look at the latest research on this compound (cas:90866-33-4).

An efficient method is described for producing both enantiomers of chiral alcs. by asym. hydrogen-transfer bioreduction of ketones in a 2-propanol (IPA)-water medium with Escherichia coli biocatalysts expressing phenylacetaldehyde reductase (PAR: wild-type and mutant enzymes) from Rhodococcus sp. ST-10 and alc. dehydrogenase from Leifsonia sp. S749 (LSADH). Also described are the detailed properties of mutant PARs, Sar268, and HAR1, which were engineered to have high activity and productivity in media composed of polar organic solvent and water, and the construction of three-dimensional structure of PAR by homol. modeling. The Km and Vmax values for some substrates and the substrate specificity of mutant PARs were quite different from those of wild-type PAR. The results well explained the increased productivity of engineered PARs in IPA-water medium.

If you want to learn more about this compound((R)-Ethyl 4-chloro-3-hydroxybutanoate)HPLC of Formula: 90866-33-4, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(90866-33-4).

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem