Final Thoughts on Chemistry for 6-Bromo-2,3-dihydrobenzofuran

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 189035-22-1

Electric Literature of 189035-22-1, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.189035-22-1, Name is 6-Bromo-2,3-dihydrobenzofuran, molecular formula is C8H7BrO. In a article,once mentioned of 189035-22-1

An asymmetric synthesis of a selective endothelin A receptor antagonist 1b is described. A highly substituted pyridine intermediate 11a was efficiently prepared via a mono-amination of inexpensive 2,6-dichloropyridine followed by a Vilsmeier formylation. Asymmetric conjugate addition of aryl lithium 14 to the chiral oxazoline 13 followed by hydrolysis afforded 15 in 90% ee. Pd(OAc)2/dppf catalyzed carbonylation followed by chemoselective addition of aryl lithium 18 gave ketone 19. Diastereoselective reduction of the ketone with LS-Selectride followed by concomitant activation of the resulting alcohol and cyclization gave the late intermediate 21. Deprotection and purification by crystallization furnished the enantiomerically pure target molecule 1b in 10% overall yield from 11a.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 189035-22-1

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H3415O – PubChem