Application of 16859-59-9, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 16859-59-9, molcular formula is C8H6O3, introducing its new discovery.
Douchi is a traditional fermented soybean food with many beneficial health effects. The aim of this study was to determine the in vitro apoptosis-inducing effect of the volatile components of Douchi (VCD) and to examine the relationship between anticancer effects and VCD. After treatment with 0.4, 0.8, and 1.6 mg/mL VCD for 48 h, the proliferation of human nasopharyngeal carcinoma CNE-1 cells was inhibited, and treatment with 1.6 mg/mL VCD had the highest inhibitory effect(84.6%). Treatment with 0.4 and 0.8 mg/mL VCD also showed good inhibitory effects with the apoptosis rates of 29.7%and 55.6%, respectively. The flow cytometry results showed that 36.2% of the 1.6 mg/mL VCD treated CNE-1 cells in the sub-G1 phase. Reversed transcription-polymerase chain reaction (RT-PCR) analysis indicated that VCD could significantly induce apoptosis in CNE-1 cancer cells (P < 0.05) by upregulating cysteine-aspartic acid protease (caspase)-3, caspase-8,caspase-9, Bax, p53, p21, E2F1, p73 and IkappaB-alpha expression and by downregulating Bcl-2, Bcl-xL, human inhibitor of apoptosis protein (HIAP)-1, HIAP-2 and NF-kappaB mRNA expression in a dose-dependent manner. VCD contained 63 chemical compounds that could potentially cause apoptosis in CNE-1 cells. These results showed that VCD had in vitro apoptosisinducing effects in CNE-1 cells, and this effect was ascribed to the complex chemical composition of VCD. The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 16859-59-9 is helpful to your research. Application of 16859-59-9
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1472O – PubChem