Extracurricular laboratory:new discovery of 1-Benzofuran-2-carbonitrile

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 41717-32-2

Application of 41717-32-2, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.41717-32-2, Name is 1-Benzofuran-2-carbonitrile, molecular formula is C9H5NO. In a Patent,once mentioned of 41717-32-2

The invention discloses a method for the catalytic oxidation of the nitrile compound of synthetic method, specific method of operation is as follows: in the ethanol solvent, are added to a reaction substrate aldehyde, NH4 OAc, alkaline agent, I2crosses oxygen uncle butanol (TBHP) and, in the 40 – 60 C lower reaction 3 – 17h after, reaction solution adding sodium thiosulfate solution stirring, then ethyl ether extraction, organic layer is separated out, reducing pressure and solvent, and then the column chromatography, using ethyl acetate/petroleum ether volume ratio 1:100 of the mixed solution is the eluant, collecting the eluant containing the compound, evaporate the solvent to obtain the product nitriles; the reaction with the alkaline additive substrate aldehyde, NH4 OAc, I2 And TBHP of the amount-of-substance ratio of 100:100 – 120:120 – 160:2 – 3:100 – 120. The synthesizing method of the invention, the beneficial effect is primarily: simple and safe operation, reaction condition is more temperate; wide range of the reaction substrate. (by machine translation)

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 41717-32-2

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H586O – PubChem