Derivation of elementary reaction about 767291-67-8

Compound(767291-67-8)Recommanded Product: (1S,2S)-N1,N2-Bis(3,3-dimethylbutyl)-N1,N2-dimethylcyclohexane-1,2-diamine received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((1S,2S)-N1,N2-Bis(3,3-dimethylbutyl)-N1,N2-dimethylcyclohexane-1,2-diamine), if you are interested, you can check out my other related articles.

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Journal of the American Chemical Society called Preparation and Reactions of Enantiomerically Pure α-Functionalized Grignard Reagents, Author is Rayner, Peter J.; O’Brien, Peter; Horan, Richard A. J., which mentions a compound: 767291-67-8, SMILESS is CN(CCC(C)(C)C)[C@@H]1[C@@H](N(CCC(C)(C)C)C)CCCC1, Molecular C20H42N2, Recommanded Product: (1S,2S)-N1,N2-Bis(3,3-dimethylbutyl)-N1,N2-dimethylcyclohexane-1,2-diamine.

A strategy for the generation of enantiomerically pure α-functionalized chiral Grignard reagents is presented. The approach involves the synthesis of α-alkoxy and α-amino sulfoxides in ≥99:1 dr and ≥99:1 er via asym. deprotonation (s-BuLi/chiral diamine) and trapping with Andersen’s sulfinate (menthol derived). Subsequent sulfoxide → Mg exchange (room temperature, 1 min) and electrophilic trapping delivers a range of enantiomerically pure α-alkoxy and α-amino substituted products. Using this approach, either enantiomer of products can be accessed in 99:1 er from asym. deprotonation protocols without the use of (-)-sparteine as the chiral ligand. Two addnl. discoveries are noteworthy: (i) for the deprotonation and trapping with Andersen’s sulfinate, there is a lack of stereospecificity at sulfur due to attack of a lithiated intermediate onto the α-alkoxy and α-amino sulfoxides as they form, and (ii) the α-alkoxy-substituted Grignard reagent is configurationally stable at room temperature for 30 min.

Compound(767291-67-8)Recommanded Product: (1S,2S)-N1,N2-Bis(3,3-dimethylbutyl)-N1,N2-dimethylcyclohexane-1,2-diamine received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((1S,2S)-N1,N2-Bis(3,3-dimethylbutyl)-N1,N2-dimethylcyclohexane-1,2-diamine), if you are interested, you can check out my other related articles.

Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem