《Synthesis and some CNS activities of new benzofuranylacryloylpiperazines》 was published in European Journal of Medicinal Chemistry in 1995. These research results belong to Dauzonne, D.; Gillardin, J. M.; Lepage, F.; Pointet, R.; Risse, S.; Lamotte, G.; Demerseman, P.. Quality Control of 6-Methoxybenzofuran-2-carbaldehyde The article mentions the following:
A series of novel [(benzofuranyl)acryloyl]piperazines, which are structurally related to both cinnamide derivatives and befuraline, have been prepared as their hydrochlorides. Their anticonvulsant and antidepressant activities against seizures induced by electroshock and against tetrabenazine-induced palpebral ptosis have been evaluated in mice. Some of them revealed interesting potencies since, although they are less active than the reference drugs, they exhibited a higher protective index. The experimental process involved the reaction of 6-Methoxybenzofuran-2-carbaldehyde(cas: 53860-74-5Quality Control of 6-Methoxybenzofuran-2-carbaldehyde)
6-Methoxybenzofuran-2-carbaldehyde(cas: 53860-74-5) belongs to benzofurans.Quality Control of 6-Methoxybenzofuran-2-carbaldehydeBenzofurans containing one furan ring that have been implicated as psychoactive recreational drugs include 6-(2-aminopropyl)benzofuran (6-APB), 5-(2-aminopropyl)benzofuran (5-APB), 5-(2-ethylaminopropyl)benzofuran (5-EAPB), and 5-methylaminopropylbenzofuran (5-MAPB).
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem