Category: benzofurans

An article Photocatalytic degradation of gaseous VOCs over Tm3+-TiO2: Revealing the activity enhancement mechanism and different reaction paths WOS:000537398200008 published article about TM-DOPED TIO2; UP-CONVERSION; GAS-PHASE; CATALYTIC-OXIDATION; OPTICAL-PROPERTIES; FACILE SYNTHESIS; ANATASE TIO2; TOLUENE; NANOPARTICLES; NANOTUBES in [Rao, Zepeng; Shi, Gansheng; Wang, Zhuang; Mahmood, Asad; Xie, Xiaofeng; Sun, Jing] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China; [Rao, Zepeng] Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China in 2020, Cited 59. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. SDS of cas: 87-41-2

In this work, we synthesized thulium (Tm3+) modified TiO2 nanoparticles by a facile sol-gel route. We show that Tm3+-modified TiO2 exhibit superior photocatalytic activity than pure TiO2 towards gas-phase degradation of acetaldehyde, o-xylene, and their mixture. The photocatalytic activity enhances with the increasing Tm content from 0.1 to 0.5 mol%. The 0.5 mol%Tm-TiO2 sample demonstrated the highest photodegradation efficiency (> 90.0%) for acetaldehyde and o-xylene. According to the systematic characterization such as photoluminescence (PL), photocurrent, up-conversion spectra, UV-Vis diffuse reflectance spectroscopy and electron spin resonance (ESR) analysis, the enhanced photocatalytic performance can be attributed to introducing the new Tm-4f states between the original band gap of TiO2, which led to the increase of efficiency of light-induced electron-hole separation and the increase of hydrophilicity which resulted in the increased adsorption capacity towards acetaldehyde and o-xylene. Gas Chromatography-Mass Spectrometer (GC-MS) analysis suggested that o-xylene was first oxidized to o-benzaldehyde, which was eventually converted to butanol before being mineralized into CO2. However, new intermediates including phthalide, o-methyl acetophenone, naphthalene and 5-Methyl-4-octanone were detected in the mixture.

SDS of cas: 87-41-2. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

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Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Sicignano, M; Schettini, R; Sica, L; Pierri, G; De Riccardis, F; Izzo, I; Maity, B; Minenkov, Y; Cavallo, L; Della Sala, G in [Sicignano, Marina; Schettini, Rosaria; Sica, Luisa; Pierri, Giovanni; De Riccardis, Francesco; Izzo, Irene; Della Sala, Giorgio] Univ Salerno, Dipartimento Chim & Biol Adolfo Zambelli, Via Giovanni Paolo II 132, I-84084 Fisciano, SA, Italy; [Maity, Bholanath; Cavallo, Luigi] KAUST, KAUST Catalysis Ctr, KCC, Thuwal 239556900, Saudi Arabia; [Minenkov, Yury] MIPT, Inst Pereulok 9, Dolgoprudnyi 141700, Moscow Region, Russia published Unprecedented Diastereoselective Arylogous Michael Addition of Unactivated Phthalides in 2019, Cited 96. Computed Properties of C8H6O2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Invited for the cover of this issue are the groups of Giorgio Della Sala at the Universita degli Studi di Salerno and Luigi Cavallo at the King Abdullah University of Science and Technology. The image depicts the transition state involved in the crown ether catalyzed arylogous Michael reaction of phthalides. Read the full text of the article at 10.1002/chem.201900168.

Welcome to talk about 87-41-2, If you have any questions, you can contact Sicignano, M; Schettini, R; Sica, L; Pierri, G; De Riccardis, F; Izzo, I; Maity, B; Minenkov, Y; Cavallo, L; Della Sala, G or send Email.. Computed Properties of C8H6O2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

In 2021 PHARMACEUTICALS-BASE published article about POSSESSING 1,4-BENZODIOXAN MOIETY; BIOLOGICAL EVALUATION; MOLECULAR DOCKING; ANTIPROLIFERATIVE ACTIVITY; CARCINOMA-CELLS; ACID SYNTHESIS; CANCER; DESIGN; INHIBITORS; IDENTIFICATION in [Stecoza, Camelia Elena; Nitulescu, George Mihai; Olaru, Octavian Tudorel] Carol Davila Univ Med & Pharm, Dept Pharmaceut Chem, Fac Pharm, 6 Traian Vuia St, Bucharest 020956, Romania; [Draghici, Constantin; Caproiu, Miron Teodor] Romanian Acad, Costin D Nenitescu Ctr Organ Chem, 202 B Splaiul Independentei, Bucharest 060023, Romania; [Bostan, Marinela; Mihaila, Mirela] Inst Virol, Ctr Immunol Stefan S Nicolau, Bucharest 030304, Romania in 2021, Cited 54. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. Safety of Isobenzofuran-1(3H)-one

In order to develop novel chemotherapeutic agents with potent anticancer activities, a series of new 2,5-diaryl/heteroaryl-1,3,4-oxadiazoles were designed and synthesized. The structures of the new compounds were established using elemental analyses, IR and NMR spectral data. The compounds were evaluated for their anticancer potential on two standardized human cell lines, HT-29 (colon adenocarcinoma) and MDA-MB-231 (breast adenocarcinoma). Cytotoxicity was measured by MTS assay, while cell cycle arrest and apoptosis assays were conducted using a flow cytometer, the results showing that the cell line MDA-MB-231 is more sensitive to the compounds’ action. The results of the predictive studies using the PASS application and the structural similarity analysis indicated STAT3 and miR-21 as the most probable pharmacological targets for the new compounds. The promising effect of compound 3e, 2-[2-(phenylsulfanylmethyl)phenyl]-5-(4-pyridyl)-1,3,4-oxadiazole, especially on the MDA-MB-231 cell line motivates future studies to improve the anticancer profile and to reduce the toxicological risks. It is worth noting that 3e produced a low toxic effect in the D. magna 24 h assay and the predictive studies on rat acute toxicity suggest a low degree of toxic risks.

Welcome to talk about 87-41-2, If you have any questions, you can contact Stecoza, CE; Nitulescu, GM; Draghici, C; Caproiu, MT; Olaru, OT; Bostan, M; Mihaila, M or send Email.. Safety of Isobenzofuran-1(3H)-one

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Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Squaramide-Catalyzed Asymmetric Intramolecular Oxa-Michael Reaction of alpha,beta-Unsaturated Carbonyls Containing Benzyl Alcohol: Construction of Chiral 1-Substituted Phthalans WOS:000649101400068 published article about ENANTIOSELECTIVE SYNTHESIS; ORGANOCATALYSTS; BOND; 1,3-DIHYDROISOBENZOFURANS; STRATEGY; CASCADE in [Son, Eun Chae; Kim, Seung Yeon; Kim, Sung-Gon] Kyonggi Univ, Coll Nat Sci, Dept Chem, Suwon 16227, South Korea in 2021, Cited 50. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. COA of Formula: C8H6O2

Organocatalytic enantioselective intramolecular oxa-Michael reactions of benzyl alcohol bearing alpha,beta-unsaturated carbonyls as Michael acceptors are presented herein. Using cinchona squaramide-based organocatalyst, enones as well as alpha,beta-unsaturated esters containing benzyl alcohol provided their corresponding 1,3-dihydroisobenzofuranyl-1-methylene ketones and 1,3-dihydroisobenzofuranyl-1-methylene esters in excellent yields with high enantioselectivities. In addition, enantioenriched 1,3-dihydroisobenzofuranyl-1-methylene ketone could be obtained from the Wittig/oxa-Michael reaction cascade of 1,3-dihydro-2-benzofuran-1-ol.

Welcome to talk about 87-41-2, If you have any questions, you can contact Son, EC; Kim, SY; Kim, SG or send Email.. COA of Formula: C8H6O2

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Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

In 2019 FITOTERAPIA published article about ENANTIOMERIC DERIVATIVES; ABSOLUTE-CONFIGURATION; DILIGUSTILIDE; UMBELLIFERAE in [Wei, Qian; Yang, Jianbo; Li, Li; Su, Yalun; Wang, Aiguo] Chinese Acad Med Sci, Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China; [Yang, Jianbo] Natl Inst Food & Drug Control, Inst Control Chinese Tradit Med & Ethn Med, Beijing 100050, Peoples R China in 2019, Cited 21. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. COA of Formula: C8H6O2

Five new phthalide dimers, chaxiongnolides C-G (1-5), the two enantiomers of riligustilide (6a and 6b) and tokinolide B (7) were isolated from the aerial parts of Ligusticum sinense Oliv cv. Chaxiong. The structures of 1-5 were elucidated through extensive spectroscopic analysis, and the relative configurations of compounds 2 and 3 were further confirmed by an X-ray diffraction experiment. The absolute configurations of 1-3 were assigned by comparing calculated and experimental ECD spectra. The ECD exciton chirality method was used to confirm the absolute configurations of compounds 4, 5, 6a and 6b. Compounds 1-3 are the first dimeric phthalides to be reported that are comprising a sedanolide unit. The compounds were evaluated in vitro for their cytotoxic activity against select human cell lines.

Welcome to talk about 87-41-2, If you have any questions, you can contact Wei, Q; Yang, JB; Li, L; Su, YL; Wang, AG or send Email.. COA of Formula: C8H6O2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Authors Liu, SL; Li, SP; Shen, XJ; Wang, YY; Du, J; Chen, BF; Han, BX; Liu, HZ in ROYAL SOC CHEMISTRY published article about COPPER(II) COMPLEXES; CATALYTIC-OXIDATION; TETRAHYDROFURAN; FUNCTIONALIZATION; CLUSTERS in [Liu, Shulin; Li, Shaopeng; Shen, Xiaojun; Wang, Yanyan; Du, Juan; Chen, Bingfeng; Han, Buxing; Liu, Huizhen] Chinese Acad Sci, Beijing Natl Lab Mol Sci, CAS Key Lab Colloid & Interface, Beijing 100190, Peoples R China; [Liu, Shulin; Li, Shaopeng; Shen, Xiaojun; Wang, Yanyan; Du, Juan; Chen, Bingfeng; Han, Buxing; Liu, Huizhen] Chinese Acad Sci, Thermodynam Inst Chem, Beijing 100190, Peoples R China; [Liu, Shulin; Li, Shaopeng; Shen, Xiaojun; Wang, Yanyan; Du, Juan; Han, Buxing; Liu, Huizhen] Univ Chinese Acad Sci, Beijing 100149, Peoples R China in 2020, Cited 40. Recommanded Product: Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Selective oxidation of ethers to lactones with O-2 as a benign oxidant using Au/CeO2 as the catalyst has been developed. The oxygen vacancies and Au-0 species on the surface of CeO2 contribute to the activation of O-2. The excellent selectivity of lactones is due to the adsorption of ethers and activation of the C(sp(3))-H bond on Au/CeO2.

Recommanded Product: Isobenzofuran-1(3H)-one. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Category: benzofurans. Recently I am researching about ISCHEMIA/REPERFUSION INJURY; INFLAMMASOME ACTIVATION; LIGUSTILIDE; STROKE; NEUROTOXICITY; PATHWAY; RATS, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [81072636, 81473219]; Sichuan Science and Technology Programs [2014JY0151, 2018SZ0015]; Fundamental Research Funds for the Central Universities, Science Foundation for Excellent Youth Scholars in Sichuan Province [2017JQ0014]; 111 Project of the National Ministry of Education [B18035]. Published in ELSEVIER in AMSTERDAM ,Authors: Li, X; Shi, MQ; Chen, C; Du, JR. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

The activation of NLRP3 inflammasome is closely related to ischemic brain injury and inhibition of NLRP3 inflammasome activation may be a new therapeutic strategy for ischemic stroke. Our previous studies showed that ligustilide (LIG) had a dose-dependent neuroprotective effect on various models of cerebral ischemia and dementia in vivo and in vitro. CD21, a kind of phthalide derivative, was modified from LIG. In this study, we established a global cerebral ischemia-reperfusion model in mice by bilateral common carotid artery ligation (2VO), and explored the neuroprotective effect of CD21 and its anti-inflammatory mechanism on cerebral ischemia mice. CD21 significantly improved weight loss, neurobehavioral deficits and neurons loss in hippocampal CA1 and caudate putamen (CPu) subregions, which were induced by 2VO in mice. CD21 significantly inhibited the overactivation of astrocyte and microglia, and decreased the mRNA level of IL-6, TNF-alpha and IL-1 beta. Moreover, CD21 significantly inhibited the activation of TLR4/NF-kappa B signaling pathway mediated by HMGB1 and NLRP3/ASC/Caspase-1 signaling pathway mediated by Cathepsin B, thus inhibiting the activation of NLRP3 inflammasome. Our results demonstrated that CD21 may exert a neuroprotection by inhibiting NLRP3 inflammasome activation after cerebral ischemia. These findings provide a new strategy for the treatment of ischemic stroke.

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Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recently I am researching about AEROBIC OXIDATION; DEHYDROGENATIVE LACTONIZATION; PALLADIUM NANOPARTICLES; ALCOHOLS; EFFICIENT; HYDROXIDE; 1,4-DIOLS; LACTONES; BEARING, Saw an article supported by the Japan Society for the Promotion of Science (JSPS)Ministry of Education, Culture, Sports, Science and Technology, Japan (MEXT)Japan Society for the Promotion of Science [18J23126]. Published in GEORG THIEME VERLAG KG in STUTTGART ,Authors: Takakura, R; Ban, K; Sajiki, H; Sawama, Y. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. Computed Properties of C8H6O2

A lactonization of various diols catalyzed by platinum on carbon (Pt/C) in water under an atmosphere of molecular oxygen was developed. Derivatives of 1,4- 1,5- and 1,6-diols were transformed into the corresponding five-, six-, and seven-membered lactones by the present oxidative lactonization method.

Computed Properties of C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Takakura, R; Ban, K; Sajiki, H; Sawama, Y or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Thermostimulated luminescence of poly(diphenylenephthalide) films. Kinetics and mechanistic steps of irradiative processes WOS:000501355900027 published article about BASIS-SET; PHTHALIDE); POLYMERS; THERMOLUMINESCENCE; MODEL; ELECTROLUMINESCENCE in [Ovchinnikov, Mikhail Yu; Antipin, Vyacheslav A.; Khursan, Sergey L.] Ufa Inst Chem UFRC RAS, 71 Prospect Oktyabrya, Ufa 450054, Russia in 2020, Cited 59. Product Details of 87-41-2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Kinetics of thermostimulated luminescence (TSL) of poly(diphenylenephthalide) (PDPh) films has been studied using mathematical modelling and DFT approximation. TSL of PDPh-film was considered to be arising from irradiative deactivation of diphenylene (DP) fragment of polymer chain in excited state formed upon recombination of the spatial separated ion-radical pairs generated by photoexcitation. Two parallel monomolecular transformations leading to excited DP have been revealed: the first path is characterized by the activation parameters of the kinetic rate constant k1 which equal to Al ti 105 sec 1 and Eat ti 70 kJ mol(-1). This path may be interpreted in terms of mechanical relaxation theory by segmental polymer mobility as electron transfer (ET) from phthalide (Ph) anion-to DP cation-radical. The second channel is supposed to be consist of two consecutive ET from triarylmethyl anion-radical to phthalide neutral (A2 ti 1 sec 1, Ea2 ti 20 kJ mol(-1)), and then to DP cation-radical (A3 N 104 sec 1, E,3 N 40 kJ mol(-1)) of the polymer chain indicating y- and fl-relaxation, respectively. The revealed mechanistic steps and electron retention efficiency estimated in B97-2/6-311 + G(d,p) approximation for the most probable anion-radicals may point out the key role of domino quantum tunneling in transfer and recombination of charges in PDPh films.

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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recently I am researching about 2-AMINOTHIAZOLE DERIVATIVES; ANTIVIRAL ACTIVITY; ALPHA; POTENT; DISCOVERY; ADIPOGENESIS; METABOLISM; BENZAMIDES; INDOLES; ACID, Saw an article supported by the . Published in PERGAMON-ELSEVIER SCIENCE LTD in OXFORD ,Authors: Mourad, AAE; Mourad, MAE. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. Recommanded Product: 87-41-2

Aims: Partial PPAR gamma agonists attracted substantially heightened interest as safer thiazolidinediones alternatives. On the other hand, Wnt/beta-catenin antagonists have been highlighted as promising strategy for type 2 diabetes management via up-regulating PPAR gamma gene expression. We aimed at synthesizing novel partial PPAR gamma agonists with beta-catenin inhibitory activity which could enhance insulin sensitivity and avoid the side effects of full PPAR gamma agonists. Main methods: We synthesized novel series of alpha-phthlimido-o-toluoyl-2-aminothiazoles hybrids for evaluating their antidiabetic activity and discovering its mechanistic pathway. We assessed effect of the new hybrids on PPAR gamma activation using a luciferase reporter assay system. Moreover, intracellular triglyceride levels, gene levels of c/EBP alpha, PPAR gamma and PPAR gamma targets including GLUT4, adiponectin, aP2 were measured in 3T3-L1 cells. Uptake of 2-DOG together with PPAR gamma and beta-catenin protein levels were evaluated in 3T3-L1cells. In addition, molecular docking studies with PPAR gamma LBD, physicochemical properties and structure activity relationship of the novel hybrids were also studied. Key findings: Three of the synthesized hybrids showed partial PPAR gamma agonistic activity and distinct PPAR gamma binding pattern. These compounds modulated PPAR gamma gene expression and PPAR gamma target genes; and increased glucose uptake in 3T3-L1 and slightly induced adipogenesis compared to rosiglitazone. Moreover, these compounds reduced beta-catenin protein level which reflected in increased both PPAR gamma gene and protein levels that leads to improved insulin sensitivity and increased GLUT4 and adiponectin gene expression. Significance: Our synthesized compounds act as novel partial PPAR gamma agonists and beta-catenin inhibitors that have potent insulin sensitizing activity and mitigate the lipogenic side effects of TZDs.

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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem