Category: benzofurans

Kraus, George A. published the artcileCoupling reactions of methoxybutenynylcopper. A facile route to substituted indoles, Safety of 2-Iodobenzofuran, the publication is Tetrahedron Letters (1978), 3195-8, database is CAplus.

Cis-MeOCH:CHCCCu with 4,2-RR¹C₆H₃I (R = NO₂, H, Me, Cl, R¹ = H; R = H, R¹ = H, NO₂; R = MeO, R¹ = NO₂) in pyridine (85-125°, 10-12 h) gave 63-94% 4,2-RR¹C₆H₃CCCH:CHOMe (I). Cis–I (R = H, R¹ = NO₂) with KOH in refluxing MeOH (4 h) gave cis– and trans-2-O₂NC₆H₄CH:C(OMe)CH₂CH(OMe)₂ which on sequential hydrolysis (aqueous MeOH, ambient temperature, yield 55%) and reduction with Al-Hg (refluxing aqueous EtOH, yield 75%) gave indole II.

Tetrahedron Letters published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Safety of 2-Iodobenzofuran.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Farmer, Jennifer L. published the artcileSolvent Choice and Kinetic Isotope Effects (KIEs) Dramatically Alter Regioselectivity in the Directed ortho Metalation (DoM) of 1,5-Dichloro-2,4-dimethoxybenzene, Quality Control of 69626-75-1, the publication is Chemistry – A European Journal (2015), 21(5), 1888-1893, database is CAplus and MEDLINE.

The regioselective formation of the 6-lithio derivative of 1,5-dichloro-2,4-dimethoxybenzene (i.e., 12) by directed ortho metalation (DoM) with nBuLi in THF is described. Although literature reports suggest direct deprotonation at C6, time-course and labeling studies revealed that deprotonation rather occurs exclusively at C3 followed by isomerization of the anion to C6. By contrast, when DoM was performed in Et₂O, deprotonation again occurred selectively at C3, but now no isomerization occurs, and electrophilic capture produces the regioisomer of that produced in THF. In these labeling studies, deuterium has an enormous kinetic isotope effect (KIE) that suppresses not only the original DoM reaction at C3 when deuterium is present there, but also suppresses isomerization to C6 when the label is at that site. Remarkably, this protecting-group role of the deuterium is unique to THF; in ether, full deprotonation of the deuterium at C3 was observed

Chemistry – A European Journal published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Quality Control of 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Olalere, Olusegun Abayomi published the artcileMicrostructural and microchemical characterization of valorized cola nitida pod wastes, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Chemical Data Collections (2020), 100356, database is CAplus.

The inherent environmental effects of the accumulated kola nut pod waste products have become a subject of discussion among many researchers. The need then arises for their alternative use as nutraceutical bioproducts. The phys. and chem. anal. techniques are often required for the standardization of these bioproducts in order to determine and maintain their quality characteristics. The dataset presented in this study provided information on the chem. profile, physisorption and thermo-anal. screening of Cola nut pod extracts Six sets of physicochem. methods were employed to characterize the phenolic extracts The result obtained clearly revealed the presence of two-hundred and fifty-five phenolic bioactive. Also presented was the thermal stability, morphol. and microstructural surface area configuration of the Cola nitida pod extracts The information obtained from this study could be used in determining the quality of food wastes bioproducts in nutria-pharmaceutical applications.

Chemical Data Collections published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Recommanded Product: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Fiandanese, Vito published the artcileAn easy access to unsymmetrically substituted 4,4′-bis-1,2,3-triazoles, Application In Synthesis of 69626-75-1, the publication is Tetrahedron (2009), 65(51), 10573-10580, database is CAplus.

A convenient synthesis of 4-alkynyl-1,2,3-triazoles and novel unsym. substituted 4,4′-bi-1,2,3-triazole derivatives has been devised starting from easily available 1-trimethylsilyl-1,3-butadiyne. The starting compound was reacted with several azides, leading to 4-(silylalkynyl)-1,2,3-triazoles, which were easily transformed into 4-arylalkynyl-1,2,3-triazoles by a Pd catalyzed coupling reaction with aryl iodides, or into novel 4,4′-bis-1,2,3-triazole derivatives by a subsequent cyclization reaction with azides.

Tetrahedron published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Application In Synthesis of 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Fiandanese, Vito published the artcileA straightforward synthesis of indole and benzofuran derivatives, Recommanded Product: 2-Iodobenzofuran, the publication is Tetrahedron (2008), 64(1), 53-60, database is CAplus.

A methodol. for the synthesis of indole and benzofuran derivatives has been devised. The starting materials, ortho-substituted aryl diynes, have been easily converted into unsaturated bis-indolyl and bis-benzofuran derivatives and into 2-ethynylindole and 2-ethynylbenzofuran. Both these products have been further elaborated into more complex unsaturated indole-benzofuran and bis-benzofuran derivatives

Tetrahedron published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Recommanded Product: 2-Iodobenzofuran.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Fiandanese, Vito published the artcileA straightforward synthesis of benzofuran- and indole-substituted 1,2,3-triazoles via click chemistry, Computed Properties of 69626-75-1, the publication is Synthesis (2009), 3853-3859, database is CAplus.

A convenient synthesis of benzofuran- and indole-substituted 1,2,3-triazoles, e.g., I (R = H, I; X = O, NH), has been devised starting from easily available 2-silylalkynyl-substituted benzofuran and indole derivatives

Synthesis published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Computed Properties of 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Mongin, Florence published the artcileDeprotonation of furans using lithium magnesates, Quality Control of 69626-75-1, the publication is Tetrahedron Letters (2005), 46(46), 7989-7992, database is CAplus.

Furan was deprotonated on treatment with 1/3 equiv of Bu₃MgLi in THF at rt. The lithium arylmagnesate formed was either trapped with electrophiles or involved in a palladium-catalyzed cross-coupling reaction with 2-bromopyridine. The highly coordinated magnesate Bu₄MgLi₂ (1/3 equiv) proved to be a better deprotonating agent than Bu₃MgLi; the monitoring of the reaction using NMR spectroscopy showed that the deprotonation of furan at rt required 2 h whereas the subsequent electrophilic trapping was instantaneous. The method was extended to benzofuran, allowing its functionalization at C2 in high yields. The deprotonation of 2-methylfuran and lithium furfurylalkoxide at C5 turned out to be difficult, requiring either long reaction times or higher temperatures

Tetrahedron Letters published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Quality Control of 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

He, Xingcun published the artcileCatalytic determination of osmium by using flow-injection analysis, Safety of 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Huaxue Tongbao (1988), 41-2, database is CAplus.

Os(VIII) was determined by flow-injection spectrophotometry (monitored at 640 nm) based on the catalytic effect of Os(VIII) on the decolorization reaction of α-naphtholphthalein and KIO₄ in borate buffer solution at pH 9.20-9.80. The catalytic reaction is a zero-order reaction. The calibration curve is linear for 0.010-0.12 μg Os/mL. The detection limit is 0.010 μg/mL. The method is accurate, simple, and with an anal. rate of 75/h. Os was determined in ore concentrates and slags with satisfactory results.

Huaxue Tongbao published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Safety of 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

He, Xingcun published the artcileFlow injection analysis of platinum metals. VI. Iridium(IV)-potassium periodate-α-naphtholphthalein system, SDS of cas: 596-01-0, the publication is Fenxi Huaxue (1990), 18(3), 237-9, database is CAplus.

A flow-injection spectrophotometric method for determination of trace Ir(IV) was developed based on the catalytic effect of Ir(IV) on the oxidation of α-naphtholphthalein with KIO₄. The detection limit is 0.020 μg Ir/mL and the anal. rate is 61 sample/h. The method is simple, fast, and sensitive.

Fenxi Huaxue published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, SDS of cas: 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Fernandez-Sanchez, J. F. published the artcileOptical CO₂-sensing layers for clinical application based on pH-sensitive indicators incorporated into nanoscopic metal-oxide supports, Synthetic Route of 596-01-0, the publication is Sensors and Actuators, B: Chemical (2007), 128(1), 145-153, database is CAplus.

We describe CO₂-selective films designed for clin. application based on the co-incorporation of different phenol dyes, α-naphtholphthalein (NAF), naphthol blue black (NBB) and Calmagite (CMG), with a phase-transfer agent, tetraoctylammonium hydroxide (TONOH), into metal-oxide nanoporous matrixes. The metal-oxide coatings consist of aluminum (AlOOH), silicon (SiO₂) and zirconium (ZrO₂) oxides. The chem. reaction principle and preparation of these new sensing layers are described in detail. We have investigated the effect of the type and concentration of the pH-indicator and TONOH together with that of the composition and morphol. characteristics of the nanostructured material. The influence of external parameters such as flow-rate, humidity and interfering gases (NO, CO, NO₂ and SO₂) were also looked into. The sensing films responded to CO₂ concentrations in the gas phase between 0.25% and 40% CO₂ (volume/volume) for NAF-TONOH, 4.1% and 30% CO₂ for NBB-TONOH and 0.6% and 40% CO₂ for CMG-TONOH, with detection limits of 0.25%, 4.1% and 0.6% CO₂ (volume/volume) for NAF-TONOH, NBB-TONOH and CMG-TONOH, resp. The nanoporous membranes provided higher dispersion and accessibility of the dye, and thus a quick response time, lower probability of aggregation, the possibility of sterilization by gamma radiation, insulation from reactive chems. and higher ambient stability.

Sensors and Actuators, B: Chemical published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Synthetic Route of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem