Category: benzofurans

Cai, Yaqi published the artcileStudies on flow injection analysis of platinum metals. III. Ruthenium(III)-potassium periodate (KIO₄)-α-naphtholphthalein system, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Fenxi Huaxue (1989), 17(3), 213-16, 212, database is CAplus.

A method was developed for the determination of trace Ru(III) by flow-injection anal. based on the catalytic effect of Ru(III) on the oxidation of α-naphtholphthalein with KIO₄ in borate buffer (pH 9-11.5). The decoloration was monitored. The proposed method is rapid, simple, and sensitive. The detection limit for Ru(III) is 0.010 μg/mL and 65 determinations can be achieved in 1 h. The method was applied to determine Ru in refined ores and slags; good results were obtained.

Fenxi Huaxue published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Name: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Cai, Yaqi published the artcileStudy on the flow injection-catalytic photometric determination of rhodium, Related Products of benzofurans, the publication is Yejin Fenxi (1991), 11(1), 34-6, database is CAplus.

In this paper, a new method is recommended for the determination of rhodium by flow injection anal. The proposed method is based on the catalytic action of Rh(III) on the oxidation of α-naphtholphthalein with KIO₄. The method is sensitive, rapid, and simple. In the concentration range of 0.020-0.40 μg/mL, rhodium can be determined at the rate of 64 per h.

Yejin Fenxi published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Related Products of benzofurans.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Sun, Jian published the artcileAntioxidant and nitrite-scavenging capacities of phenolic compounds from sugarcane (Saccharum officinarum L.) tops, Product Details of C14H10O4, the publication is Molecules (2014), 19(9), 13147-13160, 14 pp., database is CAplus and MEDLINE.

Sugarcane tops were extracted with 50% ethanol and fractionated by petroleum ether, Et acetate (EtOAc), and Bu alc. successively. Eight phenolic compounds in EtOAc extracts were purified through silica gel and Sephadex LH-20 column chromatogs., and then identified by NMR and electrospray ionization mass spectra. The results showed that eight phenolic compounds from EtOAc extracts were identified as caffeic acid, cis-p-hydroxycinnamic acid, quercetin, apigenin, albanin A, australone A, moracin M, and 5′-geranyl-5,7,2′,4′-tetrahydroxyflavone. The antioxidant and nitrite-scavenging capacities of different solvent extracts correlated pos. with their total phenolic (TP) contents. Amongst various extracts, EtOAc extracts possessed the highest TP content and presented the strongest oxygen radical absorbance capacity (ORAC), 1,1′-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging capacity, 2,2′-azobis-3-ethylbenthiaazoline-6-sulfonic acid (ABTS) radical-scavenging capacity, ferric reducing antioxidant power (FRAP) and nitrite-scavenging capacity. Thus, sugarcane tops could be promoted as a source of natural antioxidant.

Molecules published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C9H7NO2, Product Details of C14H10O4.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Kim, Ji Yeon published the artcileChemical profiles and hypoglycemic activities of mulberry leaf extracts vary with ethanol concentration, Name: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, the publication is Food Science and Biotechnology (2013), 22(5), 1-5, database is CAplus.

Five mulberry leaf extracts (water, 25, 50, 75, and 100% EtOH) were characterized for in vitro hypoglycemic activity and chem. profiles. According to chem. profiles obtained from ¹⁵Tesla Fourier transform ion cyclotron resonance mass spectrometry, water extracts contained more 1-deoxynojirimycin (DNJ) and fewer phytochems. than other extracts However, water extracts showed the highest inhibitory activity of glucose uptake. The degree of inhibition of α-glucosidase activity was similar for all extracts The effect of mulberry leaf extracts on the glucose metabolism may be attributed to addnl. or cooperative effects of DNJ with other phytochem. compounds

Food Science and Biotechnology published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Name: 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

James, Clint A. published the artcileCombined Directed ortho and Remote Metalation-Suzuki Cross-Coupling Strategies. Efficient Synthesis of Heteroaryl-Fused Benzopyranones from Biaryl O-Carbamates, Computed Properties of 69626-75-1, the publication is Journal of Organic Chemistry (2009), 74(11), 4094-4103, database is CAplus and MEDLINE.

A concise synthesis of heteroaryl-fused dibenzopyranones, e.g. I (X = O, S, NH; R = H, MeO), has been achieved by the LDA-induced migration of heterobiaryl O-carbamates, e.g. II (X = O, S, NBoc), which, in turn, were prepared in good yields using a combined directed ortho lithiation (DoM)-transition-metal-catalyzed Suzuki cross-coupling strategy. An efficient and general route to a wide variety of heterocycles including coumestans I and the previously unknown isothiocoumestan ring system has been thereby achieved.

Journal of Organic Chemistry published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Computed Properties of 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Medina-Mercado, Ignacio published the artcileGold-Catalyzed Ascorbic Acid-Induced Arylative Carbocyclization of Alkynes with Aryldiazonium Tetrafluoroborates, HPLC of Formula: 69626-75-1, the publication is ACS Catalysis (2021), 11(15), 8968-8977, database is CAplus.

Herein, arylative carbocyclization of alkynes 2-R-4-R¹-C₆H₃XCH₂CCR² (X = O, S, NTs; R = H, I; R¹ = H, OMe, Br, Ph, etc.; R² = n-Bu, Ph, thiophen-2-yl, etc.) catalyzed by gold was described. In this process, Au(I) is oxidized to Au(III) with aryldiazonium tetrafluoroborates R³C₆H₄N₂BF₄ (R³ = 4-NO₂, 3-CN, 4-C(O)OEt, etc.) following a photosensitizer-free and irradiation-free protocol. Ascorbic acid acts as a radical initiator, generating aryl radicals. According to DFT calculations, these radicals are added to Au(I), leading to a Au(II) species that is further oxidized to Au(III) with the assistance of a tetrafluoroborate anion. The overall arylative carbocyclization process is very energetically favorable, transforming arylpropargyl ethers into valuable 3,4-diaryl-2H-chromenes I in a completely regio- and stereoselective fashion. Furthermore, one of the synthesized 3,4-diaryl-2H-chromenes I exhibits polymorphism with marked differences in the color of its crystals, a property that could lead to the development of colored derivatives in the future.

ACS Catalysis published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, HPLC of Formula: 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Gundogdu, Nilufer published the artcileKinetic study for adsorption of α-naphtholphthalein onto silica gel surface-imprinted polymer and non-imprinted polymer, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, the publication is Journal of Macromolecular Science, Part A: Pure and Applied Chemistry (2016), 53(12), 734-740, database is CAplus.

In this study, the mol. imprinting polymer (MIP) was prepared using α-naphtholphthalein as a template, 2-(diethylamino)ethyl acrylate as a functional monomer and ethylene glycol dimethacrylate as a crosslinking agent by aid of free radical polymerization onto surfaces of vinyltrimethoxysilane modified silica gel. The MIP was extracted with acetonitrile for overnight to remove the template mol. from the MIP. Non-imprinted polymer (NIMP) was synthesized using the same materials except α-naphtholphthalein as template mol. α-Naphtholphthalein adsorption on surfaces of the both polymer was studied at three different temperatures (19°C, 25°C and 35°C). It was observed that the adsorption capacity increased with increasing temperature and with time. The time required to reach the equilibrium for two polymers and all temperature was accepted to be nearly 6 h. The saturated adsorption amounts at the equilibrium were found as 120 mg/g, 123 mg/g and 127 mg/g at 19°C, 25°C and 35°C, resp. for MIP and 78 mg/g, 98 mg/g and 120 mg/g at 19°C, 25°C and 35°C, resp. for NIMP. The mechanism of adsorption of α-naphtholphthalein onto MIP and NIMP is nearly appropriate to pseudo-first-order kinetic model with an activation energy of 11.63 kJ/mol for MIP and 23.69 kJ/mol for NIMP. Thermodn. parameters of activated complex in the adsorption process showed that the adsorption was carried out with an endothermic activation enthalpy, large neg. entropy changes and the pos. values of ΔG* that the adsorption processes is not favorable.

Journal of Macromolecular Science, Part A: Pure and Applied Chemistry published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Recommanded Product: 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Fuerstner, Alois published the artcileCyclobutenes by Platinum-Catalyzed Cycloisomerization Reactions of Enynes, Quality Control of 69626-75-1, the publication is Journal of the American Chemical Society (2005), 127(23), 8244-8245, database is CAplus and MEDLINE.

1,6-Enynes bearing (electron-rich) aryl substituents on their alkyne moiety rearrange to cyclobutene derivatives in the presence of catalytic amounts of PtCl₂ in toluene. The reaction is significantly accelerated when performed under an atm. of CO (1 atm), most likely by increasing the electrophilicity of the metal template by temporary coordination to this π-acidic ligand. This transformation allows the build up of considerable strain in the products as witnessed by the productive formation of tricyclic skeletons, such as 7 or 9. Moreover, these products provide evidence for the mechanistic scenario of platinum-catalyzed cycloisomerization reactions previously proposed, which are thought to proceed via organo-platinum species that mimic the reactivity of metal-complexed “nonclassical” carbocations.

Journal of the American Chemical Society published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Quality Control of 69626-75-1.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Carvajal, M. A. published the artcileHand-held optical instrument for CO₂ in gas phase based on sensing film coating optoelectronic elements, Quality Control of 596-01-0, the publication is Sensors and Actuators, B: Chemical (2010), 144(1), 232-238, database is CAplus.

Different strategies were tested to include a CO₂ optical gas sensor in a low-cost portable electronic instrument. Plastic solid-state sensor membranes are based on the quenching of a phosphorescent dye by the deprotonated form of a nonluminescent pH indicator. As a result of this study, the configuration with both optoelectronic components coated with sensing chem. (LED with the luminophore and photodetector with the pH-active dye) presents a better CO₂ response in terms of sensitivity and reproducibility than the other configurations studied by the authors. The portable measurement system resulting from the integration of coated LED with the luminophore and photodetector with the pH indicator was characterized in terms of calibration, sensitivity, short and long-term stability, transient response and thermal dependence with results comparable to laboratory instrumentation and other sensing films described in literature. The sensor calibration curve was modeled according to a theor. model, reported in the literature, with two coefficients, which was included in the microcontroller of the measurement system to provide a direct reading of the gas concentration in the display. The sensor’s full range is 0-100% CO₂ concentration The study of the response time of the membranes was made, obtaining response t₉₀ and recovery t₁₀ times of 31 and 117 s, resp. Temperature dependence was successfully fitted to an Arrhenius type function that was included in the microcontroller of the instrument, to calculate and display the CO₂ concentration, correcting the temperature dependence. The characterization demonstrated the reliability and good performance of this type of solution aimed at integrating chem. sensors in electronic and optoelectronic devices. The localization of the sensing film on the detector and on the light source makes any addnl. optical element unnecessary, thus reducing system costs, avoiding alignment problems, optimizing the efficiency of the signal collection and making it possible to replace the sensor easily.

Sensors and Actuators, B: Chemical published new progress about 596-01-0. 596-01-0 belongs to benzofurans, auxiliary class Benzofuran,Naphthalene,Alcohol,Ester, name is 3,3-Bis(4-hydroxynaphthalen-1-yl)isobenzofuran-1(3H)-one, and the molecular formula is C28H18O4, Quality Control of 596-01-0.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem

Wang, Xiao-Ling published the artcileNew phenolic compounds from the leaves of Artocarpus heterophyllus, HPLC of Formula: 56317-21-6, the publication is Chinese Chemical Letters (2017), 28(1), 37-40, database is CAplus.

One new 2-arylbenzofuran derivative, artocarstilbene B (I), one new benzaldehyde derivative, (E)-3,5-dihydroxy-4-(3-methylbut-1-enyl)benzaldehyde (II), as well as 18 known compounds (3-20) were obtained from the leaves of Artocarpus heterophyllus. Their structures were elucidated on the basis of extensive spectroscopic techniques including 2D NMR and HR-ESIMS. Many compounds exhibited moderate to weak inhibitory activity against the proliferation of the PC-3, NCI-H460, and A549 cancer cell lines.

Chinese Chemical Letters published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C22H21N3O3S, HPLC of Formula: 56317-21-6.

Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem