Archives for Chemistry Experiments of Tetrafluorophthalic anhydride

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NOVEL HYDROPHILIC AND LIPOPHILIC RHODAMINES FOR LABELLING AND IMAGING

The invention relates to novel and improved photostable rhodamine dyes of the general structural formulae I or II and their uses as fluorescent markers, e.g. for immunostainings and spectroscopic and microscopic applications, in particular in conventional and stimulated emission depletion (STED) microscopy and fluorescence correlation spectroscopy. The partially deuterated analogues are useful as molecular mass distribution tags in mass spectroscopic applications. wherein R1 = an unsubstituted or substituted alkyl group, including a cycloalkyl group, or heterocylcoalkyl group; R2 = H, an unsubstituted or substituted alkyl group, including a cycloalkyl group, or heterocycloalkyl group, or an unsubstituted or substituted aryl group or heteroaryl group, or any combination of such groups; X = CH2, C=O, C=NORa, C=NNRaNRb, CH (ORa), O, S, SO, SO2, or any other derivatives of these groups, with Ra and Rb independently being H or an organic residue, in particular an unsubstituted or substituted (cyclo) alkyl group or heterocycloalkyl group, an unsubstituted or substituted aryl group or heteroaryl group; Z = a negatively charged group with 1, 2, 3, 4 or 5 charges per anion.

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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3680O – PubChem

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Synthesis, electrochemical properties, and crystal packing of perfluororubrene

A synthesis of perfluorinated rubrene is reported. Electrochemical analysis revealed the significantly increased electron affinity of perfluororubrene compared with non-modified rubrene. Crystallographic investigation revealed two polymorphs and a solvate, each displaying twisted backbone conformations of perfluororubrene. Taken together, these results suggest perfluororubrene will find applications as a new n-type semiconductor.

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Benzofuran – Wikipedia,
Benzofuran | C8H3782O – PubChem

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Revisiting phosphorus analogues of phthalimides and naphthalimides: Syntheses and comparative studies

A series of phosphorus analogues of aromaticfused monoimides (phthalimides and naphthalimides) bearing a mesityl group on the P center have been synthesized. In a comparison of their photophysical, electrochemical, and thermal properties with those of the corresponding imides, the impact of P incorporation was revealed. Furthermore, theoretical studies using DFT methods were conducted to understand their properties.

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Benzofuran – Wikipedia,
Benzofuran | C8H3770O – PubChem

Extracurricular laboratory:new discovery of Tetrafluorophthalic anhydride

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Oxaziridinium salts as hydrophobic epoxidation reagents: Remarkable hydrophobically-directed selectivity in olefin epoxidation

Selective epoxidation of cinnamates versus crotonate was used to detect hydrophobic binding of the cinnamates in the transition states with hydrophobic oxidizing agents in water solution. With peracids as oxidants, no such effect was seen, in accord with the calculated geometries of epoxidation in which the hydrophobic groups of substrate and oxidant could not stack. However, with oxaziridinium salts carrying fused benzene rings there was significantly high selectivity for the cinnamates in water solution, which could be suppressed with added 2-propanol. The hydrophobically induced selectivity changes were even larger, in free energy terms, than those reported previously for the atom-transfer reactions in hydride reductions. Furthermore, the oxaziridinium ions could be generated with oxone from catalytic amounts of the corresponding iminium salts. These substrate selectivities should also carry over to positional selectivities in polyenes. Copyright

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Benzofuran – Wikipedia,
Benzofuran | C8H3708O – PubChem

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Blend prepared by mixing a prepolymer and a vinyl monomer and a polymer sheet obtained therefrom

Disclosed is a blend prepared by mixing a prepolymer and a vinyl monomer, wherein the prepolymer is prepared by a condensation reaction between a first compound represented by the formula Ar?H, where Ar comprises (a) a crosslinkable moiety at one end, (b) a moiety selected from the group consisting of ?O?, ?S?, ?COO?, ?CO?, ?COS?, ?SO2?, and ?NH?, and (c) one or two repeating units selected from the group consisting of: where A is carbon or nitrogen, and X is hydrogen or halogen; and a second compound consisting of an aromatic moiety. Additionally disclosed is a polymer sheet that is a crosslinked product composed of the blend.

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Benzofuran – Wikipedia,
Benzofuran | C8H3691O – PubChem

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Synthesis and Antiangiogenic Properties of Tetrafluorophthalimido and Tetrafluorobenzamido Barbituric Acids

The development of novel thalidomide derivatives as immunomodulatory and anti-angiogenic agents has revived over the last two decades. Herein we report the design and synthesis of three chemotypes of barbituric acids derived from the thalidomide structure: phthalimido-, tetrafluorophthalimido-, and tetrafluorobenzamidobarbituric acids. The latter were obtained by a new tandem reaction, including a ring opening and a decarboxylation of the fluorine-activated phthalamic acid intermediates. Thirty compounds of the three chemotypes were evaluated for their anti-angiogenic properties in an ex vivo assay by measuring the decrease in microvessel outgrowth in rat aortic ring explants. Tetrafluorination of the phthalimide moiety in tetrafluorophthalimidobarbituric acids was essential, as all of the nonfluorinated counterparts lost anti-angiogenic activity. An opening of the five-membered ring and the accompanying increased conformational freedom, in case of the corresponding tetrafluorobenzamidobarbituric acids, was well tolerated. Their activity was retained, although their molecular structures differ in torsional flexibility and possible hydrogen-bond networking, as revealed by comparative X-ray crystallographic analyses.

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Benzofuran – Wikipedia,
Benzofuran | C8H3701O – PubChem

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SUBSTITUTED ISOINDOLE-1,3-DIONES

The present invention relates to substituted isoindole-1,3-dione compounds of Formula (I) and pharmaceutically acceptable forms thereof, as E 1a/E1d adrenoreceptor modulators for the treatment of benign prostatic hypertrophy and lower urinary tract symptoms. The present invention also relates to pharmaceutical compositions comprising said new compounds, new processes to prepare these new compounds and new uses as a medicine as well as methods of treatment.

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Benzofuran – Wikipedia,
Benzofuran | C8H3675O – PubChem

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Color filter comprising Yellow Dye and Method of manufacturing the same and Display Device using the same

The present invention relates to a color filter comprising a yellow dye, a manufacturing method thereof, and a display device using the same. The yellow dye comprises a compound represented by chemical formula 1. In the chemical formula 1, R1 to R5 are independently composed of hydrogen or a C1-C20 alkyl group, and R6 to R13 are independently composed of a halogen group.

  • (CC) No baking
  • (BB) Wavelength(nm)
  • (AA) Absorbing rate
  • (FF) Baking at 230C
  • (EE) Baking at 200C
  • (DD) Baking at 180C

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Benzofuran – Wikipedia,
Benzofuran | C8H3684O – PubChem

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Synthesis, characterization, biological activity, and 3D-QSAR studies on some novel class of pyrrole derivatives as antitubercular agents

A new series of pyrrole derivatives have been designed, synthesized, and their structures have been elucidated along with the evaluation of antitubercular activity against Mycobacterium tuberculosis H37Rv using the microplate alamar blue assay method and antibacterial activity against Staphylococcus aureus, Bacillus subtilis, Klebsiella pneumoniae, and Escherichia coli by broth micro-dilution assay method. Structural activity relationships and 3D-QSAR analysis have been carried out by Topomer Comparative Molecular Field Analysis (CoMFA). Training set of 42 and test set of 8 active compounds were used to develop the method that showed cross-validated correlation coefficient (q 2) of 0.815, standard error of prediction of 0.36, non-cross-validated correlation coefficient (r 2) of 0.973, and standard error of estimate of 0.14 with six components. Graphical Abstract: Synthesis; spectral and 3D-QSAR studies; and antibacterial, antitubercular, and cytotoxic activities of a novel series of pyrrole derivatives are described.[Figure not available: see fulltext.]

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Benzofuran – Wikipedia,
Benzofuran | C8H3727O – PubChem

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TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM

Two-part cyanoacrylate compositions, methods for making same, and uses therefor are described. The compositions can be used to bond a variety of substrates including plastics and metals. The compositions remain effective after thermal ageing and humid ageing.

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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3697O – PubChem