Category: 59434-19-4

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, name: 4-Aminophthalide, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 59434-19-4, Name is 4-Aminophthalide, molecular formula is C8H7NO2

The 13C and 1H NMR spectra of several phthalides, phthalimides, phthalimidines and 1-hydroxyphthalimidines, many of them bearing an amino substituent at the aromatic ring, have been recorded and analysed.Chemical shifts were correlated by multiple linear regression analysis and substituent shift parameters were calculated.In most cases, standard deviations were lower than 0.5 ppm for 13C and 0.05 ppm for 1H spectra.Agreement between calculated and experimental shifts was satisfactory and permitted unequivocal structure assignment.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1354O – PubChem

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, name: 4-Aminophthalide, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 59434-19-4, Name is 4-Aminophthalide, molecular formula is C8H7NO2

A series of n-butylphthalide derivatives were designed and synthesized. The in vitro activities of these compounds were evaluated by a resting tension of isolated rat thoracic aorta ring assay. Compounds 4g and 4i were found to be more active than n-butylphthalide.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. name: 4-Aminophthalide, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 59434-19-4, in my other articles.

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1360O – PubChem

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 59434-19-4, name is 4-Aminophthalide, introducing its new discovery. Quality Control of 4-Aminophthalide

The nitrophthalides 3a-d aimed as intermediates in the synthesis of the title compounds 6a-d were obtained via regioselective reduction of 3-nitrophthalic anhydride 1 or by nitration of phthalide and 3,3-dimethylphthalide, respectively.Reductive methylation of the nitro groups afforded the dimethylaminophthalides 5a-d which in turn were reacted with MeMgI or in the case of 5d reduced by LiAlH4 leading finally to the title compounds.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1359O – PubChem

Application of 59434-19-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.59434-19-4, Name is 4-Aminophthalide, molecular formula is C8H7NO2. In a Article，once mentioned of 59434-19-4

Zinc phthalocyanine with PEG-400 was established as a catalytic system for chemo and regioselective reduction of aromatic nitro compounds to corresponding amines. A large range of reducible functional groups such as acid, amide, ester, halogen, lactone, nitrile, N-benzyl, O-benzyl, hydroxy and heterocycles were well tolerated. Direct synthesis of benzotriazole from O-dinitrobenzene was achieved for the first time. The present catalytic system was successfully employed for the reduction of carbonyl and ester compounds to corresponding alcohols and reductive amination of benzaldehydes with primary amines to form corresponding secondary amines. Remarkable advantages of the present catalytic method include low loading of metal, avoidance of toxic ligands and high isolated yields. The catalyst was recyclable up to four times without any loss of selectivity and activity.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 59434-19-4

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1356O – PubChem

59434-19-4, Name is 4-Aminophthalide, belongs to benzofurans compound, is a common compound. Product Details of 59434-19-4In an article, once mentioned the new application about 59434-19-4.

Provided herein are methods of treating cancer comprising administering a topoisomerase inhibitor, temozolomide, or a platin in combination with a Compound of Formula (I) or Formula (II), where the substituents Y, Z, A, B, R1, R2, R3, R4 and R5 are as defined herein.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1353O – PubChem

Reference of 59434-19-4, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.59434-19-4, Name is 4-Aminophthalide, molecular formula is C8H7NO2. In a Article，once mentioned of 59434-19-4

Copper/cobalt phthalocyanines were established for the first time as catalysts for the very efficient chemo- and regioselective reduction of aromatic nitro compounds to generate the corresponding amines. The selective reduction of nitro compounds was observed in the presence of a large range of functional groups such as aldehyde, keto, acid, amide, ester, halogen, lactone, nitrile and heterocyclic functional groups. Furthermore, the present method was found to be highly regioselective towards the reduction of aromatic dinitro compounds in a short time with high yields. In most of the cases the conversion and selectivity were >99% as monitored by GC-MS. The reduction mechanism was elucidated by UV-vis and electrospray ionization quadrupole time-of-flight tandem mass spectrometry.

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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1357O – PubChem