Archives for Chemistry Experiments of 14963-96-3

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Synthetic Route of 14963-96-3, The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature.14963-96-3, Name is 4-Methoxyisobenzofuran-1,3-dione, molecular formula is C9H6O4. In a Patent,once mentioned of 14963-96-3

The present invention provides compounds that modulate protein function, to restore protein homeostasis and/or cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions of these compounds are also provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions are also provided.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2859O – PubChem

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One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Quality Control of 4-Methoxyisobenzofuran-1,3-dione, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 14963-96-3, Name is 4-Methoxyisobenzofuran-1,3-dione, molecular formula is C9H6O4

N-Hydroxyphthalimide derivatives are readily obtained in good yields by the reaction of phthalic anhydrides with hydroxylamine hydrochloride in the presence of pyridine under microwave irradiation.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2884O – PubChem

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The present invention provides chimeric compounds of formula (II) that modulate protein function, to restore protein homeostasis, including cytokine, aiolos, and/or ikaros activity, TNF-alpha activity, CKl-alpha activity and cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions, including in combination with other cytokine and inflammatory mediators, are provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions, such as cytokine-mediated diseases, disorders, and conditions, including inflammation, fibromyalgia, rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, psoriasis, psoriatic arthritis, inflammatory bowel diseases, Crohn’s disease, ulcerative colitis, uveitis, inflammatory lung diseases, chronic obstructive pulmonary disease, Alzheimer’s disease, organ transplant rejection, and cancer, are provided.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2845O – PubChem

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Phenethylsulfones substituted in the position alpha to the phenyl group with a 1-oxoisoindoline or 1,3-dioxoisoindoline group reduce the levels of TNFalpha in a mammal. Typical embodiments are 2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-aminoisoindoline-1,3-dione and 2-[1-(3-cyclopentyloxy-4-methoxyphenyl)-2-methylsulfonylethyl]isoindoline-1,3-dione.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2857O – PubChem

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Application of 14963-96-3, A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 14963-96-3, Name is 4-Methoxyisobenzofuran-1,3-dione, molecular formula is C9H6O4. In a Patent,once mentioned of 14963-96-3

1-Oxo- and 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)isoindolines substituted in the 4- and/or 7-position of the isoindoline ring and optionally further substituted in the 3-position of the 2,6-dioxopiperidine ring reduce the levels of inflammatory cytokines such as TNFalpha in a mammal. A typical embodiment is 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2851O – PubChem

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Related Products of 14963-96-3, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Article, and a compound is mentioned, 14963-96-3, 4-Methoxyisobenzofuran-1,3-dione, introducing its new discovery.

Condensations of stabilized phosphorane 1 with 3-substituted phthalic anhydrides were investigated.The importance of various effects influencing regio- and stereoselectivity of these reactions is discussed.It is proposed that the oxygen atom on the substituents in position 3 can act as a Lewis base toward the electron-deficient phosphorus of the ylid.The resulting complexation stabilizes the transition state for the reacction at the ortho carbonyl group, thus offsetting the usual steric and “push” effects, wich favour attack at the meta carbonyl function. – Key words: Wittig condensations, phthalic anhydrides, regioselectivity, stereoselectivity.

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Reference:
Benzofuran – Wikipedia,
Benzofuran | C8H2867O – PubChem

More research is needed about 14963-96-3

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Synthesis of phosphonate 3-phthalidyl esters as prodrugs for potential intracellular delivery of phosphonates

A new prodrug approach for intracellular delivery of phosphonates was developed via the synthesis of 3-phthalidyl esters of 1- naphthalenemethylphosphonate. This approach is advantageous over the traditional acyloxymethyl phosphonate prodrugs, because these prodrugs do not generate formaldehyde and have improved plasma half-lives.

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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2868O – PubChem

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Facile Interconversion of the Isomeric Acid Chlorides Derived from Half Methyl Esters of 3-Methoxyphthalic Acid

The isomeric acid chlorides obtained by treating the half methyl esters of 3-methoxyphthalic acid with thionyl chloride interconvert so readily that it is not practical to isolate one acid chloride free of the other.At equilibrium the main isomer is the acid chloride derived from 1-methyl ester.When either half ester is treated with thionyl chloride at 20 deg C for 2 h and the crude acid chloride so formed treated with 1,4-dimethoxybenzene in the presence of stannic chloride the only benzophenone derivative obtained is that derived from the more stable acid chloride.

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Benzofuran – Wikipedia,
Benzofuran | C8H2872O – PubChem

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14963-96-3, Name is 4-Methoxyisobenzofuran-1,3-dione, belongs to benzofuran compound, is a common compound. COA of Formula: C9H6O4In an article, once mentioned the new application about 14963-96-3.

Rhein synthesis process (by machine translation)

The invention relates to a synthesis process of Rhein. In order to 2, 3 – dimethyl phenol as raw materials, acetate ester, oxidation shall be 3 – methoxy neighbouring benzene dicarboxylic acid, acid anhydride bitter wine dehydration by b, then the excess methyl methyl anisole in aluminum trichloride under the action of the product after fu ke reaction, then the sulfuric acid cyclization and get intermediate large […], rhubarb the phenol passes through acetylation treatment, re-oxidation of the double because vinegar switzerland, finally deacetylation synthesizing a large yellow acid. (by machine translation)

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Benzofuran – Wikipedia,
Benzofuran | C8H2852O – PubChem

The Absolute Best Science Experiment for 4-Methoxyisobenzofuran-1,3-dione

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In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 14963-96-3, name is 4-Methoxyisobenzofuran-1,3-dione, introducing its new discovery. Computed Properties of C9H6O4

BENZODIOXANE DERIVATIVES AND THEIR PHARMACEUTICAL USE

Compounds of formula (I): wherein Ra and Rb are as defined in the claims, exhibit alpha2C antagonistic activity and are thus useful as alpha2C antagonists.

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Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2850O – PubChem