Category: 13099-95-1

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. HPLC of Formula: C11H10O4. Introducing a new discovery about 13099-95-1, Name is Ethyl 3-oxo-2,3-dihydrobenzofuran-2-carboxylate

Diastereo- and enantioselective propargylation of benzofuranones catalyzed by pybox-copper complex

Diastereo- and enantioselective preparation of 2,2-disubstituted benzofuran-3(2H)-one has been realized by a pybox-copper catalyzed reaction between 2-substituted benzofuran-3(2H)-one and propargyl acetate. The utility of this method was demonstrated by further transformation of the terminal alkyne into a methyl ketone without loss of enantiomeric purity.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.HPLC of Formula: C11H10O4, you can also check out more blogs about13099-95-1

Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H3515O – PubChem

Electric Literature of 13099-95-1, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 13099-95-1, Name is Ethyl 3-oxo-2,3-dihydrobenzofuran-2-carboxylate,introducing its new discovery.

Stereodivergent Synthesis of 3-Aminooxindole Derivatives Containing Vicinal Tetrasubstituted Stereocenters via the Mannich Reaction

A highly enantioselective stereodivergent synthesis of 3-aminooxindole derivatives was accomplished via asymmetric Mannich reaction between 2-substituted benzofuran-3-one and isatin-derived ketimines. Both anti and syn-selective chiral 3,3-disubstituted amino oxindoles bearing two adjacent tetrasubstituted stereogenic centers with high yield and excellent enantioselectivities were obtained using readily available cinchona-alkaloid derived organocatalysts. The control experiment revealed that oxygen atom present in the benzofuran ring played an important role in switching diastereodivergence. The obtained Mannich product was further transformed into a biologically important 2,3-dihydrobenzofuran derivative having three contiguous stereocenters with no loss of enantioselectivity.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 13099-95-1, and how the biochemistry of the body works.Electric Literature of 13099-95-1

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Benzofuran – Wikipedia,
Benzofuran | C8H3506O – PubChem

13099-95-1, Ethyl 3-oxo-2,3-dihydrobenzofuran-2-carboxylate is a benzofuran compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

General procedure: A 10-mL glass tube equipped with a stirring bar was charged with benzofuranone 1 (0.60 mmol, 1.5 equiv), nitroallylic acetate 2 (0.40 mmol, 1 equiv), the catalyst K (0.04 mmol, 10 mol %), and CH2Cl2 (4.0 mL). The resulting solution was stirred at rt for 12 h. The solvent was evaporated under reduced pressure and the crude product was directly purified by flash column chromatography (PE/EtOAc from 20:1 to15:1) to provide the desired products 3., 13099-95-1

The synthetic route of 13099-95-1 has been constantly updated, and we look forward to future research findings.

Reference£º
Article; Zhao, Long; Raabe, Gerhard; Enders, Dieter; Synthesis; vol. 51; 6; (2019); p. 1391 – 1398;,
Benzofuran – Wikipedia
Benzofuran | C8H6O – PubChem