Chemistry is traditionally divided into organic and inorganic chemistry. name: Ethyl benzofuran-2-carboxylate, The former is the study of compounds containing at least one carbon-hydrogen bonds.In a patent，Which mentioned a new discovery about 3199-61-9
A series of benzofuran-2-carboxamide-N-benzyl pyridinium halide derivatives (6a-o) are synthesized as new cholinesterase inhibitors. The synthetic pathway involves the reaction of salicylaldehyde derivatives and ethyl bromoacetate, followed by hydrolysis and amidation with 3- and 4-picolyl amine. Subsequently, N-((pyridin-4-yl) methyl) benzofuran-2-carboxamide and substituted N-((pyridin-3-yl) methyl) benzofuran-2-carboxamides reacts with benzyl halides to afford target compounds (6a-o). The chemical structures of all derivatives were confirmed by spectroscopic methods. The studies reveal that some of the synthesized compounds are potent butyrylcholinesterase inhibitors with IC50 values in the range of 0.054?2.7 muM. In addition, good inhibitory effects on Abeta self-aggregation are observed for 6h and 6k (33.1 and 46.4% at 100 muM, respectively).
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Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H2997O – PubChem