4412-91-3, Name is 3-Furanmethanol, molecular formula is C5H6O2, Formula: C5H6O2, belongs to benzofurans compound, is a common compound. In a patnet, author is Zaher, Ahmed M., once mentioned the new application about 4412-91-3.
New antimicrobial and cytotoxic benzofuran glucoside fromSenecio glaucusL
The ethyl acetate fraction of the dried aerial parts ofSenecio glaucusL. exhibited significant antimicrobial activity against some of selected bacteria and fungi. Also, it showed potent cytotoxicity against PANC-1 cancer cell lines under glucose deficient medium. The ethyl acetate fraction was subjected to different chromatographic techniques for isolation of the bioactive compounds. A new benzofuran glucoside; 2,3-dihydro-3 beta-hydroxyeuparin 3-O-glucopyranoside (1) was isolated. Additionally, two known flavonoid compounds isorhamentin 3-O-beta-D-glucoside (2), and isorhamentin 3-O-beta-D-rutinoside (3) were first identified inS. glaucus. Compound1exhibited potent antimicrobial activities against two Gram-positive bacteria, one Gram-negative bacteria, and two fungi. Also, it displayed potent cytotoxic activity against PANC-1 cancer cell lines under glucose deficient medium (IC50 7.5 mu M). However, the isolated flavonoid glycosides (2&3) showed moderate antimicrobial activities against two Gram-positive bacteria, two Gram-negative bacteria, four fungi, and did not show any cytotoxic activity against PANC-1.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 4412-91-3 help many people in the next few years. Formula: C5H6O2.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem