Carboxylic esters as radical leaving groups: a new and efficient gas-phase synthesis of benzofurans was written by Black, Michael;Cadogan, J. I. G.;Cartwright, Gary A.;McNab, Hamish;MacPherson, Andrew D.. And the article was included in Journal of the Chemical Society, Chemical Communications in 1993.Related Products of 1646-27-1 This article mentions the following:
Flash vacuum pyrolysis (FVP) of 2-allyloxycinnamate esters gives benzofurans in high yield, via cyclization of a phenoxyl radical and subsequent cleavage of the carboxylic ester function; coumarins are obtained by FVP of the corresponding phenols. Flash vacuum pyrolysis of Me 3-[2-(allyloxy)phenyl]-2-propenoate (I) gave benzofuranone (II) in 68% yield. In cases where lower yields were obtained, coumarins were the major products. In the experiment, the researchers used many compounds, for example, Methyl benzofuran-2-carboxylate (cas: 1646-27-1Related Products of 1646-27-1).
Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives. Benzofurans are compounds with a planar structure having 10 pi electrons that include the lone pair on oxygen atom, which makes it more susceptible to electrophilic attack. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Related Products of 1646-27-1
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem