Reference of 6296-53-3, Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics.In a document type is Patent, and a compound is mentioned, 6296-53-3, N-(1,3-Dioxo-1,3-dihydroisobenzofuran-4-yl)acetamide, introducing its new discovery.
The present invention provides an improved process for preparation of pure N-(2-(l-(3- ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)-l,3-dioxoisoindolin-4-yl)acetamide (1) (commonly known as Apremilast); wherein the content of des-acetyl apremilast (la) is less than 1% w/w and having total amount of genotoxic substances less than 25 ppm; comprising the steps of reacting the compound l-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethan- 1-amine (A) or its chiral acid salt with N-(l,3-dioxo-l,3-dihydroisobenzofuran-4-yl)-acetamide (B) in presence of ether or amide solvent and optionally, in presence of an acid; followed by the treatment with an acetylating agent.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.Reference of 6296-53-3. In my other articles, you can also check out more blogs about 6296-53-3
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3437O – PubChem