Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. name: 2,3-Dihydrobenzofuran-5-amine. Introducing a new discovery about 42933-43-7, Name is 2,3-Dihydrobenzofuran-5-amine
The direct C-H amination of arenes is an important strategy to streamline the discovery and preparation of functional molecules. Herein, we report an operationally simple arene C-H amination reaction that, in contrast to most literature precedent, affords directly the synthetically versatile primary aniline products without relying on protecting group manipulations. Inexpensive Fe(II)-sulfate serves as a convenient catalyst for the transformation. The reaction tolerates a wide scope of arenes, including structurally complex drugs. Importantly, the arene substrates are used as limiting reagents in the transformation. This operationally simple transformation should considerably accelerate the discovery of medicines and functional molecules.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.name: 2,3-Dihydrobenzofuran-5-amine, you can also check out more blogs about42933-43-7