13099-95-1, Name is Ethyl 3-oxo-2,3-dihydrobenzofuran-2-carboxylate, belongs to benzofurans compound, is a common compound. Recommanded Product: 13099-95-1In an article, once mentioned the new application about 13099-95-1.
N-Myristoyltransferase (NMT) is an attractive antiprotozoan drug target. A lead-hopping approach was utilized in the design and synthesis of novel benzo[b]thiophene-containing inhibitors of Plasmodium falciparum (Pf) and Plasmodium vivax (Pv) NMT. These inhibitors are selective against Homo sapiens NMT1 (HsNMT), have excellent ligand efficiency (LE), and display antiparasitic activity in vitro. The binding mode of this series was determined by crystallography and shows a novel binding mode for the benzothiophene ring.
Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 13099-95-1
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H3501O – PubChem