Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, Recommanded Product: 497-23-4497-23-4, Name is Furan-2(5H)-one, SMILES is O=C1OCC=C1, belongs to benzofurans compound. In a article, author is Caliskan, Zerrin Zerenler, introduce new discover of the category.
Synthesis of New 4-Oxo-Tetrahydroindol Derivatives by Using Chemical and Microbial Biotransformation Methods
An efficient method for the preparation of 4-oxo-4,5,6,7-tetrahydroindoles was successfully applied to the synthesis of N-substituted 4-oxo-4,5,6,7-tetrahydroindoles (4) and (5) for the first time. Manganese(III) acetate-mediated acetoxylation of (2) produced 4,5,6,7-tetrahydro-4-oxo-7,7-dimethyl benzofuran-5-yl acetate (3) for the first time in the literature. Then 4,5,6,7-tetrahydro-4-oxo-7,7-dimethyl benzofuran-5-yl acetate was converted to its indole derivative (4) via benzyl amine. Thus, 1-benzyl-5-hydroxy-7,7-dimethyl-6,7-dihydro-1H-indol-4(5H)-one (4) was obtained in good yields. Furthermore, biotransformation of pharmacologically interesting compounds such as 5-hydroxy-7,7-dimethyl-6,7-dihydro-1H-indol-4-(5H)-one (5) were also obtained by biotransformation reaction using Aspergillus niger.
Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 497-23-4. Recommanded Product: 497-23-4.
Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem