A new application about 496-41-3

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.name: Benzofuran-2-carboxylic acid, you can also check out more blogs about496-41-3

Chemistry is an experimental science, and the best way to enjoy it and learn about it is performing experiments. name: Benzofuran-2-carboxylic acid. Introducing a new discovery about 496-41-3, Name is Benzofuran-2-carboxylic acid

In order to find novel nonhydroxamate histone deacetylase (HDAC) inhibitors, a series of thiol-based compounds modeled after suberoylanilide hydroxamic acid (SAHA) was synthesized, and their inhibitory effect on HDACs was evaluated. Compound 6, in which the hydroxamic acid of SAHA was replaced by a thiol, was found to be as potent as SAHA, and optimization of this series led to the identification of HDAC inhibitors more potent than SAHA.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions.name: Benzofuran-2-carboxylic acid, you can also check out more blogs about496-41-3

Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H1981O – PubChem