Reference of 23681-89-2, Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 23681-89-2, molcular formula is C8H8O2, introducing its new discovery.
Methionine aminopeptidase 2 (MetAP2) is an enzyme that cleaves an N-terminal methionine residue from a number of newly synthesized proteins. Pre-clinical and clinical studies suggest that MetAP2 inhibitors could be used as a novel treatment for obesity. Herein we describe our use of fragment screening methods and structural biology to quickly identify and elaborate an indazole fragment into a series of reversible MetAP2 inhibitors with <10 nM potency, excellent selectivity, and favorable in vitro safety profiles. The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 23681-89-2 is helpful to your research. Reference of 23681-89-2
Reference：
Benzofuran – Wikipedia,
Benzofuran | C8H580O – PubChem