In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 652-39-1, name is 4-Fluoroisobenzofuran-1,3-dione, introducing its new discovery. Product Details of 652-39-1
Tumor necrosis factor-alpha production enhancing activity of substituted 3′-methylthalidomide: Influence of substituents at the phthaloyl moiety on the activity and stereoselectivity
The synthesis and tumor necrosis factor (TNF)-alpha production enhancing activity of substituted 3′-methyl-thalidomides on human leukemia cell line HL-60 stimulated with 12-O-tetradecanoyl-phorbol 13-acetate (TPA) are described. Though the introduction of an electron-donating amino group at the phthaloyl moiety of alpha-methylthalidomides enhanced the activity, substituted alpha-methylthalidomides showed decreased stereoselectivity as compared to that of non-substituted alpha-methylthalidomide. The data indicates that the TNF-alpha production enhancing activity of thalidomide derivatives depends on both the electronic-state of substituents at the fused benzene ring and the stereochemistry of the glutarimide moiety.
We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 652-39-1, and how the biochemistry of the body works.Product Details of 652-39-1
Reference£º
Benzofuran – Wikipedia,
Benzofuran | C8H2544O – PubChem