Heterocyclic Building Block-benzofuran

Authors Sakurai, M; Kawakami, R; Kihara, N in PERGAMON-ELSEVIER SCIENCE LTD published article about N,N-DIMETHYLFORMAMIDE; ALLYLATION; ACYLATION; SECONDARY; PEPTIDES; AMINES; ACIDS; MILD in [Sakurai, Masayoshi; Kawakami, Rina; Kihara, Nobuhiro] Kanagawa Univ, Fac Sci, Dept Chem, 2946 Tsuchiya, Hiratsuka, Kanagawa 2591293, Japan in 2019, Cited 34. Recommanded Product: Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Hydrazides and amines were N-formylated by DMF in the presence of tert-butyldimethylsilyl triflate (TBSOTf) at room temperature, in good to excellent yields. (C) 2019 Elsevier Ltd. All rights reserved.

Recommanded Product: Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Sakurai, M; Kawakami, R; Kihara, N or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recently I am researching about C-H BONDS; RACEMIC SECONDARY ALCOHOLS; HYDROGEN-PEROXIDE; ASYMMETRIC EPOXIDATION; OXOCARBENIUM IONS; AEROBIC OXIDATION; HYDROXYLATION; MECHANISM; COMPLEX; DESYMMETRIZATION, Saw an article supported by the National Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21722204, 21971148]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Sun, ST; Ma, YG; Liu, ZQ; Liu, L. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. Product Details of 87-41-2

A manganese-catalyzed oxidative kinetic resolution of cyclic benzylic ethers through asymmetric C(sp(3))-H oxidation is reported. The practical approach is applicable to a wide range of 1,3-dihydroisobenzofurans bearing diverse functional groups and substituent patterns at the alpha position with extremely efficient enantiodiscrimination. The generality of the strategy was further demonstrated by efficient oxidative kinetic resolution of another type of five-membered cyclic benzylic ether, 2,3-dihydrobenzofurans, and six-membered 6H-benzo[c]chromenes. Direct late-stage oxidative kinetic resolution of bioactive molecules that are otherwise difficult to access was further explored.

Product Details of 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Sun, ST; Ma, YG; Liu, ZQ; Liu, L or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article A comparative study of nitrobenzene reduction using model catalysts WOS:000456147000005 published article about OXIDATIVE DEHYDROGENATION; CARBON NANOTUBES; LIQUID-PHASE; EFFICIENT; GRAPHENE; HYDROGENATION; CARBOCATALYST; NITROARENES; OXIDE; BN in [Wu, Shuchang] Taizhou Univ, Sch Pharmaceut & Mat Engn, Taizhou 318000, Zhejiang, Peoples R China; [Lin, Yangming; Wen, Guodong; Liu, Hongyang; Su, Dang Sheng] Chinese Acad Sci, Shenyang Natl Lab Mat Sci, Inst Met Res, 72 Wenhua Rd, Shenyang 110016, Peoples R China; [Zhong, Bingwei] Zhejiang A&F Univ, JiYang Coll, 77 Puyang Rd, Zhuji 311800, Peoples R China in 2019, Cited 28. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. Name: Isobenzofuran-1(3H)-one

A zigzag-type quinone performs better than an armchair-type quinone in the reduction of nitrobenzene. When different kinds of functionalities co-exist, the reaction is dominated by the most active sites, but the most negative sites should also be taken into consideration if the acitive sites have zigzag structures.

Name: Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Wu, SC; Lin, YM; Zhong, BW; Wen, GD; Liu, HY; Su, DS or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recommanded Product: 87-41-2. I found the field of Chemistry very interesting. Saw the article Biomimetic systems involving sequential redox reactions in glycolysis – the sulfur effect published in 2020, Reprint Addresses Ogawa, N (corresponding author), Meiji Univ, Dept Appl Chem, Kawasaki, Kanagawa 2148571, Japan.; Kanomata, N (corresponding author), Waseda Univ, Dept Chem & Biochem, Shinjuku Ku, Tokyo 1698555, Japan.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one.

Magnesium hemithioacetates were used as model cysteine compounds to mimic natural hemithioacetals, and their biomimetic oxidation reactions using a model NAD(+) compound were investigated. Cyclic hemithioacetate was found to be the best substrate for the reaction with the model NAD(+) compound, which gave the corresponding NADH analog in excellent yield.

Recommanded Product: 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Ogawa, N; Furukawa, S; Kosugi, Y; Takazawa, T; Kanomata, N or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

I found the field of Biochemistry & Molecular Biology; Entomology; Physiology very interesting. Saw the article Mode of action of 3-butylidene phthalide as a competent natural pesticide published in 2020. Formula: C8H6O2, Reprint Addresses Safaie, N (corresponding author), Tarbiat Modares Univ, Fac Agr, Dept Plant Pathol, POB 14115-336, Tehran, Iran.. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

In this study, the biological activities and mode of action of 3-butylidene phthalide (3-BPH) were studied. 3-BPH had a superior efficiency against microsclerotia of Macrophomina phaseolina compared to the commercial fungicide tricyclazole. The microsclerotia formation and pigmentation were inhibited at 100 mu g/mL. Moreover, the fungicide exhibited in silico affinity toward trihydroxy naphthalene reductase (3HNR). Both 3-BPH and tricyclazole showed congruence in the orientation and interaction within the 3HNR active site. 3-BPH displayed a strong interaction with SER-164, TYR-178, and TYR-223, with estimated binding energy and inhibition constant of -6.78 kcal mol(-1), and Ki = 12.6 mu M, respectively. Furthermore, it showed in vitro and in silico inhibitory activity against Drosophila melanogaster acetylcholinesterase in a concentration-dependent manner with IC50 = 730 mu g/mL. It also impaired Galleria mellonella phenol oxidase enzyme, which corresponds with the insect’s immune system. Phytotoxicity of 3-BPH was evident against Lemna minor at 1000 mu g/mL; nevertheless, it was nontoxic at the concentrations inhibiting M. phaseolina microsclerotia and dark pigments suggest that it may be safe for use on other plants at low doses. Further assays are wanted to develop 3-BPH as a novel crop protection compound.

Formula: C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Abbod, M; Safaie, N; Gholivand, K; Mehrabadi, M; Bonsaii, M or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Pd-Catalyzed Dehydrogenative Oxidation of Alcohols to Functionalized Molecules WOS:000481979500029 published article about OXIDANT-FREE OXIDATION; CARBOXYLIC-ACID SALTS; ASTERISK-IR COMPLEX; SECONDARY ALCOHOLS; HOMOGENEOUS RUTHENIUM; HYDROGEN-PRODUCTION; N-ALKYLATION; ACCEPTORLESS; PALLADIUM; LIGAND in [Mori, Takamichi] Sanyo Onoda City Univ, Fac Engn, Dept Appl Chem, 1-1-1 Daigakudori, Yamaguchi 7560884, Japan; [Ishii, Chihiro; Kimura, Masanari] Nagasaki Univ, Grad Sch Engn, 1-14 Bunkyo Machi, Nagasaki 8528521, Japan in 2019, Cited 63. Recommanded Product: Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

A dehydrogenative oxidation reaction of primary alcohols to aldehydes catalyzed by a simple Pd/Xantphos catalytic system was developed under an argon or nitrogen atmosphere without oxidizing agents or hydrogen acceptors. The reaction product could be easily changed: under aerobic conditions, esters were obtained in aprotic solvents, whereas the corresponding carboxylic acids were produced in aqueous media. These oxidizing processes were applicable to the efficient synthesis of useful nitrogen-containing heterocyclic compounds such as indole, quinazoline, and benzimidazole via intramolecular versions of this reaction from amino alcohols.

Recommanded Product: Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Mori, T; Ishii, C; Kimura, M or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Recommanded Product: Isobenzofuran-1(3H)-one. In 2019 ORG PROCESS RES DEV published article about OXIDANT-FREE OXIDATION; CARBOXYLIC-ACID SALTS; ASTERISK-IR COMPLEX; SECONDARY ALCOHOLS; HOMOGENEOUS RUTHENIUM; HYDROGEN-PRODUCTION; N-ALKYLATION; ACCEPTORLESS; PALLADIUM; LIGAND in [Mori, Takamichi] Sanyo Onoda City Univ, Fac Engn, Dept Appl Chem, 1-1-1 Daigakudori, Yamaguchi 7560884, Japan; [Ishii, Chihiro; Kimura, Masanari] Nagasaki Univ, Grad Sch Engn, 1-14 Bunkyo Machi, Nagasaki 8528521, Japan in 2019, Cited 63. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

A dehydrogenative oxidation reaction of primary alcohols to aldehydes catalyzed by a simple Pd/Xantphos catalytic system was developed under an argon or nitrogen atmosphere without oxidizing agents or hydrogen acceptors. The reaction product could be easily changed: under aerobic conditions, esters were obtained in aprotic solvents, whereas the corresponding carboxylic acids were produced in aqueous media. These oxidizing processes were applicable to the efficient synthesis of useful nitrogen-containing heterocyclic compounds such as indole, quinazoline, and benzimidazole via intramolecular versions of this reaction from amino alcohols.

Recommanded Product: Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Mori, T; Ishii, C; Kimura, M or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

SDS of cas: 87-41-2. Recently I am researching about INTRAMOLECULAR SPIROCYCLIZATION; MOLECULES; NANOSCOPY, Saw an article supported by the ETH ZurichETH Zurich [ETH-0216-1]. Published in NATURE PUBLISHING GROUP in LONDON ,Authors: Halabi, EA; Pinotsi, D; Rivera-Fuentes, P. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one

Photoswitchable molecules have multiple applications in the physical and life sciences because their properties can be modulated with light. Fluxional molecules, which undergo rapid degenerate rearrangements in the electronic ground state, also exhibit switching behavior. The stochastic nature of fluxional switching, however, has hampered its application in the development of functional molecules and materials. Here we combine photoswitching and fluxionality to develop a fluorophore that enables very long (>30 min) time-lapse single-molecule localization microscopy in living cells with minimal phototoxicity and no apparent photobleaching. These long time-lapse experiments allow us to track intracellular organelles with unprecedented spatiotemporal resolution, revealing new information of the three-dimensional compartmentalization of synaptic vesicle trafficking in live human neurons.

SDS of cas: 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Halabi, EA; Pinotsi, D; Rivera-Fuentes, P or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Application In Synthesis of Isobenzofuran-1(3H)-one. Authors Liang, XY; Yu, P; Fu, C; Shen, YC in PERGAMON-ELSEVIER SCIENCE LTD published article about in [Liang, Xiayu; Yu, Peng; Fu, Chen; Shen, Yongcun] Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, 122 Luoshi Rd, Wuhan 430070, Peoples R China in 2021, Cited 31. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

A new strategy for the facile synthesis of hydroxyalkylamides through the ring-opening reaction of lactone with amine promoted by dibutyltin acetate was developed. A series of hydroxyalkylamide compounds were obtained and the method was successfully applied to the synthesis of pharmaceutically active molecules tyrosinase inhibitor V and HDAC inhibitor VI via a three-step synthetic pathway. The broad substrate scope, mild reaction conditions and practical application proved the effectiveness, compatibility and practicality of this method. (C) 2021 Elsevier Ltd. All rights reserved.

Application In Synthesis of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Liang, XY; Yu, P; Fu, C; Shen, YC or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

In 2019 SYNLETT published article about AEROBIC OXIDATION; DEHYDROGENATIVE LACTONIZATION; PALLADIUM NANOPARTICLES; ALCOHOLS; EFFICIENT; HYDROXIDE; 1,4-DIOLS; LACTONES; BEARING in [Takakura, Ryoya; Ban, Kazuho; Sajiki, Hironao; Sawama, Yoshinari] Gifu Pharmaceut Univ, Lab Organ Chem, 1-25-4 Daigaku Nishi, Gifu 5011196, Japan in 2019, Cited 49. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. Recommanded Product: 87-41-2

A lactonization of various diols catalyzed by platinum on carbon (Pt/C) in water under an atmosphere of molecular oxygen was developed. Derivatives of 1,4- 1,5- and 1,6-diols were transformed into the corresponding five-, six-, and seven-membered lactones by the present oxidative lactonization method.

Recommanded Product: 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Takakura, R; Ban, K; Sajiki, H; Sawama, Y or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem