Heterocyclic Building Block-benzofuran

Zou, J; Chen, GD; Zhao, H; Wang, XX; Zhang, ZJ; Qu, YB; He, RR; So, KF; Yao, XS; Gao, H in [Zou, Jian; Chen, Guo-Dong; Wang, Xiao-Xia; He, Rong-Rong; Yao, Xin-Sheng; Gao, Hao] Jinan Univ, Inst Tradit Chinese Med & Nat Prod, Coll Pharm, Guangdon Prov Key Lab Pharmacodynam Constituents, Guangzhou 510632, Guangdong, Peoples R China; [Zou, Jian] Jinan Univ, Integrated Chinese & Western Med Postdoctoral Res, Guangzhou 510632, Guangdong, Peoples R China; [Zhao, Huan] Jinan Univ, Coll Tradit Chinese Med, Guangzhou 510632, Guangdong, Peoples R China; [Zhang, Zai-Jun; So, Kwok-Fai] Jinan Univ, Inst New Drug Res, Coll Pharm, Guangzhou Key Lab Innovat Chem Drug Res Cardiocer, Guangzhou 510632, Guangdong, Peoples R China; [Qu, Yi-Bo] Jinan Univ, GMH Inst Cent Nervous Syst Regenerat, Guangdong Med Key Lab Brain Funct & Dis, Guangzhou 510632, Guangdong, Peoples R China published Triangeliphthalides A-D: bioactive phthalide trimers with new skeletons from Angelica sinensis and their production mechanism in 2019, Cited 18. Category: benzofurans. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Triangeliphthalides A-D (1-4), four novel phthalide trimers with two new linkage styles, were isolated from Angelica sinensis, together with two related phthalide dimers (5-6). Their structures including absolute configurations were determined. The production mechanism of phthalide polymers was proposed, and their bioactivities were also evaluated.

Category: benzofurans. Welcome to talk about 87-41-2, If you have any questions, you can contact Zou, J; Chen, GD; Zhao, H; Wang, XX; Zhang, ZJ; Qu, YB; He, RR; So, KF; Yao, XS; Gao, H or send Email.

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Benzofuran – Wikipedia,
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An article A comparative study of nitrobenzene reduction using model catalysts WOS:000456147000005 published article about OXIDATIVE DEHYDROGENATION; CARBON NANOTUBES; LIQUID-PHASE; EFFICIENT; GRAPHENE; HYDROGENATION; CARBOCATALYST; NITROARENES; OXIDE; BN in [Wu, Shuchang] Taizhou Univ, Sch Pharmaceut & Mat Engn, Taizhou 318000, Zhejiang, Peoples R China; [Lin, Yangming; Wen, Guodong; Liu, Hongyang; Su, Dang Sheng] Chinese Acad Sci, Shenyang Natl Lab Mat Sci, Inst Met Res, 72 Wenhua Rd, Shenyang 110016, Peoples R China; [Zhong, Bingwei] Zhejiang A&F Univ, JiYang Coll, 77 Puyang Rd, Zhuji 311800, Peoples R China in 2019, Cited 28. Safety of Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

A zigzag-type quinone performs better than an armchair-type quinone in the reduction of nitrobenzene. When different kinds of functionalities co-exist, the reaction is dominated by the most active sites, but the most negative sites should also be taken into consideration if the acitive sites have zigzag structures.

Welcome to talk about 87-41-2, If you have any questions, you can contact Wu, SC; Lin, YM; Zhong, BW; Wen, GD; Liu, HY; Su, DS or send Email.. Safety of Isobenzofuran-1(3H)-one

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Benzofuran – Wikipedia,
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Takahashi, I; Nishiwaki, Y; Saitoh, K; Matsunaga, T; Aratake, A; Morita, T; Hosoi, S in [Takahashi, Ichiro; Nishiwaki, Yoshinori; Saitoh, Kenta; Matsunaga, Takatoshi; Aratake, Akihiro; Morita, Toshio] Univ Fukui, Fac Engn, Dept Appl Chem & Biotechnol, Bunkyo Ku, Fukui 9108507, Japan; [Hosoi, Shinzo] Kyoto Pharmaceut Univ, Res Ctr Pharm Educ, Yamashina Ku, 5 Nakauchi Cho, Kyoto 6078414, Japan published EXPLORATION OF MODERATE CONDITIONS AND SUBSTRATE VARIATION IN THE DIRECT CONDENSATION BETWEEN PHTHALIDE AND PRIMARY AMINE CATALYZED BY GaCl3. ARE ALIPHATIC AMINES LESS REACTIVE THAN AROMATIC ONES? in 2019, Cited 38. Category: benzofurans. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Direct condensation between phthalide and a primary amine in the presence of Lewis acid was achieved for the first time in organic solvent-diluted reaction systems catalyzed by GaCl3. The peripheral aspects of this reaction is discussed.

Category: benzofurans. Welcome to talk about 87-41-2, If you have any questions, you can contact Takahashi, I; Nishiwaki, Y; Saitoh, K; Matsunaga, T; Aratake, A; Morita, T; Hosoi, S or send Email.

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,Benzofuran | C8H6O – PubChem

In 2019 BIOMED PHARMACOTHER published article about TRADITIONAL CHINESE MEDICINE; CORONARY-HEART-DISEASE; UP-REGULATION; ATHEROGENESIS; CHOLESTEROL; ACTIVATION; MACROPHAGE in [Lei, Wei; Deng, Yan-Fang; Hu, Xue-Yan; Jiang, Min; Bai, Gang] Nankai Univ, Coll Pharm, State Key Lab Med Chem Biol, Haihe Educ Pk,38 Tongyan Rd, Tianjin 300353, Peoples R China; [Lei, Wei; Deng, Yan-Fang; Hu, Xue-Yan; Jiang, Min; Bai, Gang] Nankai Univ, Tianjin Key Lab Mol Drug Res, Haihe Educ Pk,38 Tongyan Rd, Tianjin 300353, Peoples R China; [Ni, Jia-Nan] Tianjing Univ Tradit Chinese Med, Coll Tradit Chinese Med, Tianjin 300193, Peoples R China in 2019, Cited 36. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. Name: Isobenzofuran-1(3H)-one

Atherosclerosis is initiated by the local inflammation response to lipid deposition, and the most commonly administered antiatherogenic drugs are statins. Based on traditional Chinese medicine (TCM) evidence, we aimed to find effective therapeutic agents other than statins. A TCM, Suxiao Jiuxin Pill (SX), has been widely used in curing cardiovascular diseases for thirty years. In this paper, a combination of pharmacologic studies and RNA-Seq transcriptomics were employed to explore the pharmacodynamic advantages of SX over atorvastatin in the ApoE(-/-) mouse. 113 differentially expressed genes that were modulated by SX to a greater degree than atorvastatin were primarily involved in immunomodulation. The expression of BTK, AKT1, c-jun and CD137 was effectively regulated by SX with better effect than atorvastatin. Then a dual-luciferase reporter assay for NF-kappa B inhibition was applied to identify active components in SX. As a result, Senkyunolide A (Sen A) and Ligustilide (Lig), the key immunomodulatory ingredients in SX, were found to inhibit the expression of CD137 which is a diagnostic biomarker in atherosclerosis. It was further confirmed that Lig effectively suppressed the expression of AP-1 and NF-kappa B and the phosphorylation of AKT. Therefore, Lig achieved its CD137 inhibition through suppressing the expression of AP-1 and AKT/NF-kappa B signaling pathway, which partly explains the immunomodulation of SX in atherosclerosis. Above all, phthalides may be the primary components of SX improving immune and inflammation response in atherosclerosis.

Name: Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Lei, W; Deng, YF; Hu, XY; Ni, JN; Jiang, M; Bai, G or send Email.

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Product Details of 87-41-2. In 2019 PLOS ONE published article about NATURAL MELANIN; HUMIC ACIDS; BIOSYNTHESIS; IDENTIFICATION; OPTIMIZATION; METABOLITES; POLYMERS; SPECTRA; CULTURE in [Suwannarach, Nakarin; Kumla, Jaturong; Lumyong, Saisamorn] Chiang Mai Univ, Dept Biol, Fac Sci, Chiang Mai, Thailand; [Suwannarach, Nakarin; Kumla, Jaturong; Lumyong, Saisamorn] Chiang Mai Univ, Ctr Excellence Microbial Divers & Sustainable Uti, Chiang Mai, Thailand; [Watanabe, Bunta] Kyoto Univ, Inst Chem Res, Kyoto, Japan; [Matsui, Kenji] Yamaguchi Univ, Grad Sch Sci & Technol Innovat Agr, Yamaguchi, Japan; [Lumyong, Saisamorn] Royal Soc Thailand, Acad Sci, Bangkok, Thailand in 2019, Cited 61. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Melanin is a natural pigment that is produced by filamentous fungi. In this study, the endophytic species, Spissiomyces endophytica (strain SDBR-CMU319), produced a brownblack pigment in the mycelia. Consequently, the pigment was extracted from the dried fungal biomass. This was followed by pigment purification, characterization and identification. Physical and chemical characteristics of the pigment showed acid precipitation, alkali solubilization, decolorization with oxidizing agents, and insolubility in most organic solvents and water. The pigment was confirmed as melanin based on ultraviolet-visible spectroscopy, Fourier-transform infrared, and electron paramagnetic resonance spectra analyses. The analyses of the elemental composition indicated that the pigment possessed a low percentage of nitrogen, and therefore, was not 3,4-dihydroxyphenylalanine melanin. Inhibition studies involving specific inhibitors, both tricyclazole and phthalide, and suggest that fungal melanin could be synthesized through the 1,8-dihydroxynaphthalene pathway. The optimum conditions for fungal pigment production from this species were investigated. The highest fungal pigment yield was observed in glucose yeast extract peptone medium at an initial pH value of 6.0 and at 25 degrees C over three weeks of cultivation. This is the first report on the production and characterization of melanin obtained from the genus Spissiomyces.

Welcome to talk about 87-41-2, If you have any questions, you can contact Suwannarach, N; Kumla, J; Watanabe, B; Matsui, K; Lumyong, S or send Email.. Product Details of 87-41-2

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Recently I am researching about FLUORESCENT-PROBES; CELL; FLUOROPHORE; MICROSCOPY, Saw an article supported by the Department of Optical Nanoscopy. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Butkevich, AN. The CAS is 87-41-2. Through research, I have a further understanding and discovery of Isobenzofuran-1(3H)-one. Safety of Isobenzofuran-1(3H)-one

A modular synthetic approach toward diverse analogues of the far-red fluorophore silicon-rhodamine (SiR), based on a regioselective double nucleophilic addition of aryllanthanum reagents to esters, anhydrides, and lactones, is proposed. The reaction has improved functional group tolerance and represents a unified strategy toward cell-permeant, spontaneously blinking, and photoactivatable SiR fluorescent labels. In tandem with Pd-catalyzed hydroxy- or aminocarbonylation, it serves a streamlined synthetic pathway to a series of validated live-cell-compatible fluorescent dyes.

Safety of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Butkevich, AN or send Email.

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Benzofuran – Wikipedia,
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An article Coal tar- and residual oil-derived porous carbon as metal-free catalyst for nitroarene reduction to aminoarene WOS:000450312600056 published article about ACTIVATED CARBON; SELECTIVE HYDROGENATION; GRAPHENE OXIDE; NITROGEN; OXIDATION; NITROBENZENE; NANOTUBES; PERFORMANCE; SITES; ELECTRODES in [Wei, Qinhong; Qin, Fangfang; Shen, Wenzhong] Chinese Acad Sci, Inst Coal Chem, State Key Lab Coal Convers, Taiyuan 030001, Shanxi, Peoples R China; [Ma, Qingxiang] Ningxia Univ, State Key Lab High Efficiency Coal Utilizat & Gre, Yinchuan 750021, Peoples R China in 2019, Cited 57. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. SDS of cas: 87-41-2

Nitroarenes reduction is an important technology in the industrial production of aminoarenes. In this work, we presented an environment-friendly and low-cost green synthesis route for preparation of oxygen and nitrogen co-doped porous carbon (ONPC) via acid oxidation and alkali activation methods using coal tar- and residual oil-based as starting materials, and the prepared ONPC was employed as metal-free carbon catalyst for nitroarenes reduction to aminoarenes in the presence of hydrazine hydrate. This ONPC catalyst showed much higher catalytic activity as compared to those of un-doped porous carbon (PC), activated carbon (AC) and carbon black, which was attributed to its large surface area and developed pore structure as well as O and N co-doping. Additionally, it also exhibited a versatility in various aromatic nitro-compounds reduction to relative aromatic amines. Experimental results by using model catalysts to simulate different carbons with various oxygen-containing groups proved that carbonyl groups were more favorable for nitrobenzene reduction to aniline. Upon co-doping O and N into PC, the two kinds of introduced species synergistically promoted the catalytic activity of PC. Good performance together with low-cost preparation makes oxygen and nitrogen co-doped porous carbon a potential substitution of supported metal catalyst for nitroarenes reduction. (C) 2018 Elsevier Ltd. All rights reserved.

SDS of cas: 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Wei, QH; Qin, FF; Ma, QX; Shen, WZ or send Email.

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Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Category: benzofurans. Authors Mourad, AAE; Khodir, AE; Saber, S; Mourad, MAE in MDPI published article about in [Mourad, Ahmed A. E.] Port Said Univ, Fac Pharm, Pharmacol & Toxicol Dept, Port Said 42511, Egypt; [Khodir, Ahmed E.] Horus Univ, Fac Pharm, Pharmacol Dept, New Damietta 34518, Egypt; [Saber, Sameh] Delta Univ Sci & Technol, Fac Pharm, Pharmacol Dept, Mansoura 11152, Dakahlia, Egypt; [Mourad, Mai A. E.] Port Said Univ, Fac Pharm, Med Chem Dept, Port Said 42511, Egypt in 2021, Cited 55. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Background: Dipeptidyl peptidase-4 (DPP-4) inhibitors have emerged as anti-hyperglycemic agents that improve glycemic control in type 2 diabetic patients, either as monotherapy or in combination with other antidiabetic drugs. Methods: A novel series of dihydropyrimidine phthalimide hybrids was synthesized and evaluated for their in vitro and in vivo DPP-4 inhibition activity and selectivity using alogliptin as reference. Oral glucose tolerance test was assessed in type 2 diabetic rats after chronic treatment with the synthesized hybrids +/- metformin. Cytotoxicity and antioxidant assays were performed. Additionally, molecular docking study with DPP-4 and structure activity relationship of the novel hybrids were also studied. Results: Among the synthesized hybrids, 10g, 10i, 10e, 10d and 10b had stronger in vitro DPP-4 inhibitory activity than alogliptin. Moreover, an in vivo DPP-4 inhibition assay revealed that 10g and 10i have the strongest and the most extended blood DPP-4 inhibitory activity compared to alogliptin. In type 2 diabetic rats, hybrids 10g, 10i and 10e exhibited better glycemic control than alogliptin, an effect that further supported by metformin combination. Finally, 10j, 10e, 10h and 10d had the highest radical scavenging activity in DPPH assay. Conclusions: Hybrids 10g, 10i and 10e are potent DPP-4 inhibitors which may be beneficial for T2DM treatment.

Category: benzofurans. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

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An article Photocatalytic degradation of gaseous VOCs over Tm3+-TiO2: Revealing the activity enhancement mechanism and different reaction paths WOS:000537398200008 published article about TM-DOPED TIO2; UP-CONVERSION; GAS-PHASE; CATALYTIC-OXIDATION; OPTICAL-PROPERTIES; FACILE SYNTHESIS; ANATASE TIO2; TOLUENE; NANOPARTICLES; NANOTUBES in [Rao, Zepeng; Shi, Gansheng; Wang, Zhuang; Mahmood, Asad; Xie, Xiaofeng; Sun, Jing] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China; [Rao, Zepeng] Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China in 2020, Cited 59. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. COA of Formula: C8H6O2

In this work, we synthesized thulium (Tm3+) modified TiO2 nanoparticles by a facile sol-gel route. We show that Tm3+-modified TiO2 exhibit superior photocatalytic activity than pure TiO2 towards gas-phase degradation of acetaldehyde, o-xylene, and their mixture. The photocatalytic activity enhances with the increasing Tm content from 0.1 to 0.5 mol%. The 0.5 mol%Tm-TiO2 sample demonstrated the highest photodegradation efficiency (> 90.0%) for acetaldehyde and o-xylene. According to the systematic characterization such as photoluminescence (PL), photocurrent, up-conversion spectra, UV-Vis diffuse reflectance spectroscopy and electron spin resonance (ESR) analysis, the enhanced photocatalytic performance can be attributed to introducing the new Tm-4f states between the original band gap of TiO2, which led to the increase of efficiency of light-induced electron-hole separation and the increase of hydrophilicity which resulted in the increased adsorption capacity towards acetaldehyde and o-xylene. Gas Chromatography-Mass Spectrometer (GC-MS) analysis suggested that o-xylene was first oxidized to o-benzaldehyde, which was eventually converted to butanol before being mineralized into CO2. However, new intermediates including phthalide, o-methyl acetophenone, naphthalene and 5-Methyl-4-octanone were detected in the mixture.

COA of Formula: C8H6O2. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

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Benzofuran – Wikipedia,
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Authors Monsigny, L; Thuery, P; Berthet, JC; Cantat, T in AMER CHEMICAL SOC published article about RING-OPENING POLYMERIZATION; METAL-FREE; CRYSTAL-STRUCTURE; REDUCTIVE DEPOLYMERIZATION; CARBONYL-COMPOUNDS; ALDOL CONDENSATION; SYMMETRIC ETHERS; CARBOXYLIC-ACIDS; CYCLOTRIMERIZATION; ETHERIFICATION in [Monsigny, Louis; Thuery, Pierre; Berthet, Jean-Claude; Cantat, Thibault] Univ Paris Saclay, CEA Saclay, CNRS, NIMBE,CEA, F-91191 Gif Sur Yvette, France in 2019, Cited 76. Recommanded Product: Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

We report herein the possibility to perform the hydrosilylation of carbonyls using actinide complexes as catalysts. While complexes of the uranyl ion [UO2](2+) have been poorly considered in catalysis, we show the potentialities of the Lewis acid [UO2(OTf)(2)] (1) in the catalytic hydrosilylation of a series of aldehydes. [UO2(OTf)(2)] proved to be a very active catalyst affording distinct reduction products depending on the nature of the reductant. With Et3SiH, a number of aliphatic and aromatic aldehydes are reduced into symmetric ethers, while (Pr3SiH)-Pr-i yielded silylated alcohols. Studies of the reaction mechanism led to the isolation of aldehyde/uranyl complexes, [UO2(OTf)(2)(4-Me2N-PhCHO)(3)], [UO2(mu-kappa(2)-OTf)(2)(PhCHO)](n), and [UO2(mu-kappa(2)-OTf(kappa(1)-OTf)(PhCHO)(2)](2), which have been fully characterized by NMR, IR, and single-crystal X-ray diffraction.

Recommanded Product: Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Monsigny, L; Thuery, P; Berthet, JC; Cantat, T or send Email.

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Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem