Oxidative cyclization of 3-oxopropanenitriles mediated manganese(III) acetate with 2-thienyl substituted alkenes was written by Yilmaz, Mehmet;Uzunalioglu, Nese;Yakut, Mehtap;Pekel, A. Tarik. And the article was included in Turkish Journal of Chemistry in 2008.Electric Literature of C10H8O3 This article mentions the following:
The oxidative cyclization of 3-oxopropanenitriles with alkenes containing 2-thienyl group by manganese(III) acetate was studied. Treatment of 3-oxopropanenitriles with 2-[(E)-2-phenylvinyl]thiophene gave 4-phenyl-5-(2-thienyl)-4,5-dihydrofuran-3-carbonitriles in moderate yields (52%-60%). 5-(2-Thienyl) substituted 4,5-dihydrofuran-3-carbonitriles were obtained by the oxidative cyclization of these 3-oxopropanenitriles with 2-[(E)-1-methyl-2-phenylvinyl]thiophene in good yields (54%-68%). In addition, the reactions of 2-(1-phenylvinyl)thiophene with various 3-oxopropanenitriles produced 4,5-dihydrofurans containing heterocycle in 77%-91% yields. In the experiment, the researchers used many compounds, for example, Methyl benzofuran-2-carboxylate (cas: 1646-27-1Electric Literature of C10H8O3).
Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives. Benzofurans are only weakly aromatic in nature and they are cleaved by many oxidative and reductive conditions. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Electric Literature of C10H8O3
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem