Tag: M.W=100-150

An article Syntheses of o-iodobenzyl alcohols-BODIPY structures as potential precursors of bimodal tags for positron emission tomography and optical imaging WOS:000504779400003 published article about ONE-POT SYNTHESIS; ARYLDIAZONIUM SALTS; EXPEDIENT SYNTHESIS; FLUORESCENCE; PET; CHEMISTRY; DYES; DERIVATIVES; MONOXIDE; DESIGN in [Christine, Thifanie; Tabey, Alexis; Cornilleau, Thomas; Fouquet, Eric; Hermange, Philippe] Univ Bordeaux, CNRS, Bordeaux INP, ISM,UMR 5255, 351 Cours Liberat, F-33405 Talence, France in 2019, Cited 77. Recommanded Product: 87-41-2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Aiming the faster development from bench to bedside of new potential tracers, multimodal tracers for positron emission tomography (PET) and optical imaging (OI) have emerged as a very promising tool. Indeed, they combine the simplicity of use of optical techniques for in vitro/in vivo pre-clinical studies with the various clinical possibilities offered by PET imaging using their radioactive versions. In this context, the preparation of new tags detectable by fluorescence imaging and potentially suitable for PET imaging after a last-step C-11-labeling of the corresponding precursor has been investigated. Various designs and syntheses were explored by linking o-iodobenzyl alcohols and tetramethyl-BODIPY moieties together. Among them, the most promising structure was produced in 30% yield over five steps from a commercially available and inexpensive starting material. (C) 2019 Elsevier Ltd. All rights reserved.

Welcome to talk about 87-41-2, If you have any questions, you can contact Christine, T; Tabey, A; Cornilleau, T; Fouquet, E; Hermange, P or send Email.. Recommanded Product: 87-41-2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article Photocatalytic degradation of gaseous VOCs over Tm3+-TiO2: Revealing the activity enhancement mechanism and different reaction paths WOS:000537398200008 published article about TM-DOPED TIO2; UP-CONVERSION; GAS-PHASE; CATALYTIC-OXIDATION; OPTICAL-PROPERTIES; FACILE SYNTHESIS; ANATASE TIO2; TOLUENE; NANOPARTICLES; NANOTUBES in [Rao, Zepeng; Shi, Gansheng; Wang, Zhuang; Mahmood, Asad; Xie, Xiaofeng; Sun, Jing] Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, 1295 Dingxi Rd, Shanghai 200050, Peoples R China; [Rao, Zepeng] Univ Chinese Acad Sci, 19 A Yuquan Rd, Beijing 100049, Peoples R China in 2020, Cited 59. Computed Properties of C8H6O2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

In this work, we synthesized thulium (Tm3+) modified TiO2 nanoparticles by a facile sol-gel route. We show that Tm3+-modified TiO2 exhibit superior photocatalytic activity than pure TiO2 towards gas-phase degradation of acetaldehyde, o-xylene, and their mixture. The photocatalytic activity enhances with the increasing Tm content from 0.1 to 0.5 mol%. The 0.5 mol%Tm-TiO2 sample demonstrated the highest photodegradation efficiency (> 90.0%) for acetaldehyde and o-xylene. According to the systematic characterization such as photoluminescence (PL), photocurrent, up-conversion spectra, UV-Vis diffuse reflectance spectroscopy and electron spin resonance (ESR) analysis, the enhanced photocatalytic performance can be attributed to introducing the new Tm-4f states between the original band gap of TiO2, which led to the increase of efficiency of light-induced electron-hole separation and the increase of hydrophilicity which resulted in the increased adsorption capacity towards acetaldehyde and o-xylene. Gas Chromatography-Mass Spectrometer (GC-MS) analysis suggested that o-xylene was first oxidized to o-benzaldehyde, which was eventually converted to butanol before being mineralized into CO2. However, new intermediates including phthalide, o-methyl acetophenone, naphthalene and 5-Methyl-4-octanone were detected in the mixture.

Computed Properties of C8H6O2. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Renzetti, A; Fukumoto, K in [Renzetti, Andrea; Fukumoto, Kozo] Univ Ryukyus, Fac Educ, 1 Senbaru, Nishihara, Okinawa 9030213, Japan published Synthesis of Phthalides and alpha,beta-butenolides by Transition Metal-Catalyzed Activation of CH Bonds in 2019, Cited 68. Formula: C8H6O2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Phthalides and ,-butenolides are two related classes of oxygenated heterocycles with a wide range of biological activities. An innovative strategy to prepare these compounds is based on CH bond functionalization reactions, in which two simple, unfunctionalized molecules are coupled together with cleavage of a CH bond and formation of a CX bond (X=C or heteroatom). This paper reviews the methods for the synthesis of phthalides and ,-butenolides by CH bond functionalization from non-halogenated starting materials. Over 30 methods are reported, mostly developed during the past ten years.

Formula: C8H6O2. Welcome to talk about 87-41-2, If you have any questions, you can contact Renzetti, A; Fukumoto, K or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

An article The role of melanin in the grapevine trunk disease pathogen Lasiodiplodia gilanensis WOS:000607189100011 published article about LATENT PATHOGENS; FUNGAL MELANINS; BIOSYNTHESIS; BOTRYOSPHAERIACEAE; TRICYCLAZOLE; IDENTIFICATION; PENETRATION; GROWTH; MELANIZATION; APPRESSORIA in [Airam Rangel-Montoya, Edelweiss; Hernandez-Martinez, Rufina] Ctr Invest Cient & Educ Super Ensenada CICESE, Dept Microbiol, Ensenada 22860, Baja California, Mexico; [Paolinelli, Marcos] Inst Nacl Tecnol Agr INTA, Estn Expt Agr Mendoza, San Martin 3853, RA-5534 Mendoza, Argentina; [Paolinelli, Marcos] Consejo Nacl Invest Cient & Tecn, Buenos Aires, DF, Argentina; [Rolshausen, Philippe] Univ Calif Riverside, Dept Bot & Plant Sci, Riverside, CA 92521 USA in 2020, Cited 69. SDS of cas: 87-41-2. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Lasiodiplodia (Botryosphaeriaceae) includes fungi that are considered among the most aggressive to grapevine, capable of causing cankers and necrotic lesions which eventually lead to death of host plants. A common characteristic of this genus is the presence of melanin in conidia and mycelium. Melanin is produced by the oxidation of phenolic and/or indolic compounds. For some fungi, this pigment is an essential factor for pathogenicity. This study characterized the types and the roles of melanin produced by Lasiodiplodia gilanensis. Using specific melanin inhibitors, L. gilanensis was shown to synthesize DOPA-melanin, DHN-melanin, and pyomelanin. DOPA-melanin was shown to be involved in production of aerial mycelium and protection against enzymatic lysis and oxidative stress; DHN-melanin to be involved in ramification of mycelium when exposed to nutrient deficiency; and pyomelanin to be related with hyphae development. The fungus used tyrosine as a precursor of DOPA-melanin and as carbon and nitrogen sources, and produced melanin inside the piths of infected plants. Genes involved in melanin synthesis were conserved among the Botryosphaeriaceae, highlighting the importance of melanin in this family.

SDS of cas: 87-41-2. Welcome to talk about 87-41-2, If you have any questions, you can contact Rangel-Montoya, EA; Paolinelli, M; Rolshausen, P; Hernandez-Martinez, R or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

In 2019 CHINESE CHEM LETT published article about ONE-POT SYNTHESIS; O-PHTHALALDEHYDE; HYDROGENATION; DOMINO; ALCOHOLS; SOLVENT; ESTERS; COMPLEXES; HYDRIDE; LIGANDS in [Liu, Bin; Zhou, Xigeng] Fudan Univ, Dept Chem, Shanghai Key Lab Mol Catalysis & Innovat Mat, Shanghai 200433, Peoples R China; [Liu, Bin] Technol Res Insititute Shanghai Huayi Grp Co, Shanghai 200241, Peoples R China in 2019, Cited 54. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. HPLC of Formula: C8H6O2

An efficient method for preparation of substituted 1,2-phenylenedimethanols and aliphatic 1,4-diols that are valuable intermediates in organic synthesis, has been developed by the base-promoted reduction of isobenzofuran-1(3H)-ones and y-lactones with silane under mild conditions. Compared with traditional procedures using stoichiometric amounts of metal hydrides and alkyl reductants, the present method avoids the use of sensitive reagents and is operationally simple and a broad variety of functional groups are tolerated. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.

Welcome to talk about 87-41-2, If you have any questions, you can contact Liu, B; Zhou, XG or send Email.. HPLC of Formula: C8H6O2

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

SDS of cas: 87-41-2. In 2020 ANGEW CHEM INT EDIT published article about CHANNEL ORGANIC SEMICONDUCTORS; PI-CONJUGATED MATERIALS; HIGH-PERFORMANCE; BUILDING-BLOCK; THIOPHENE-S,S-DIOXIDIZED INDOPHENINE; QUINOIDAL OLIGOTHIOPHENES; SIDE-CHAIN; MOLECULES; POLYMERS; ANALOGS in [Du, Tian; Gao, Ruiheng; Deng, Yunfeng; Wang, Cheng; Zhou, Qian; Geng, Yanhou] Tianjin Univ, Sch Mat Sci & Engn, Tianjin 300072, Peoples R China; [Deng, Yunfeng; Geng, Yanhou] Tianjin Univ, Tianjin Key Lab Mol Optoelect Sci, Tianjin 300072, Peoples R China; [Deng, Yunfeng; Geng, Yanhou] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China; [Geng, Yanhou] Tianjin Univ, Joint Sch Natl Univ Singapore & Tianjin Univ, Int Campus, Fuzhou 350207, Fujian, Peoples R China in 2020, Cited 46. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

A series of 1,3-indandione-terminated pi-conjugated quinoids were synthesized by alkoxide-mediated rearrangement reaction of the respective alkene precursors, followed by air oxidation. This new protocol allows access to quinoidal compounds with variable termini and cores. The resulting quinoids all show LUMO levels below -4.0 eV and molar extinction coefficients above 10(5) L mol(-1) cm(-1). The optoelectronic properties of these compounds can be regulated by tuning the central cores as well as the aryl termini ascribed to the delocalized frontier molecular orbitals over the entire molecular skeleton involving aryl termini. n-Channel organic thin-film transistors with electron mobility of up to 0.38 cm(2) V-1 s(-1) were fabricated, showing the potential of this new class of quinoids as organic semiconductors.

SDS of cas: 87-41-2. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Authors Sicignano, M; Schettini, R; Sica, L; Pierri, G; De Riccardis, F; Izzo, I; Maity, B; Minenkov, Y; Cavallo, L; Della Sala, G in WILEY-V C H VERLAG GMBH published article about VINYLOGOUS ALDOL REACTION; PHASE-TRANSFER CATALYSIS; GAUSSIAN-BASIS SETS; ASYMMETRIC-SYNTHESIS; PHTHALIDE-3-CARBOXYLIC ACID; ENANTIOSELECTIVE ADDITION; MACROCYCLIC POLYETHERS; ANNULATION REACTIONS; DENSITY FUNCTIONALS; ENOLATE ACTIVATORS in [Sicignano, Marina; Schettini, Rosaria; Sica, Luisa; Pierri, Giovanni; De Riccardis, Francesco; Izzo, Irene; Della Sala, Giorgio] Univ Salerno, Dipartimento Chim & Biol Adolfo Zambelli, Via Giovanni Paolo II 132, I-84084 Fisciano, SA, Italy; [Maity, Bholanath; Cavallo, Luigi] KAUST, KAUST Catalysis Ctr, KCC, Thuwal 239556900, Saudi Arabia; [Minenkov, Yury] MIPT, Inst Pereulok 9, Dolgoprudnyi 141700, Moscow Region, Russia in 2019, Cited 96. Application In Synthesis of Isobenzofuran-1(3H)-one. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2

Invited for the cover of this issue are the groups of Giorgio Della Sala at the Universita degli Studi di Salerno and Luigi Cavallo at the King Abdullah University of Science and Technology. The image depicts the transition state involved in the crown ether catalyzed arylogous Michael reaction of phthalides. Read the full text of the article at 10.1002/chem.201900168.

Application In Synthesis of Isobenzofuran-1(3H)-one. Welcome to talk about 87-41-2, If you have any questions, you can contact Sicignano, M; Schettini, R; Sica, L; Pierri, G; De Riccardis, F; Izzo, I; Maity, B; Minenkov, Y; Cavallo, L; Della Sala, G or send Email.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Category: benzofurans. In 2019 FITOTERAPIA published article about ENANTIOMERIC DERIVATIVES; ABSOLUTE-CONFIGURATION; DILIGUSTILIDE; UMBELLIFERAE in [Wei, Qian; Yang, Jianbo; Li, Li; Su, Yalun; Wang, Aiguo] Chinese Acad Med Sci, Peking Union Med Coll, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing 100050, Peoples R China; [Yang, Jianbo] Natl Inst Food & Drug Control, Inst Control Chinese Tradit Med & Ethn Med, Beijing 100050, Peoples R China in 2019, Cited 21. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Five new phthalide dimers, chaxiongnolides C-G (1-5), the two enantiomers of riligustilide (6a and 6b) and tokinolide B (7) were isolated from the aerial parts of Ligusticum sinense Oliv cv. Chaxiong. The structures of 1-5 were elucidated through extensive spectroscopic analysis, and the relative configurations of compounds 2 and 3 were further confirmed by an X-ray diffraction experiment. The absolute configurations of 1-3 were assigned by comparing calculated and experimental ECD spectra. The ECD exciton chirality method was used to confirm the absolute configurations of compounds 4, 5, 6a and 6b. Compounds 1-3 are the first dimeric phthalides to be reported that are comprising a sedanolide unit. The compounds were evaluated in vitro for their cytotoxic activity against select human cell lines.

Category: benzofurans. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

Product Details of 87-41-2. Patil, A; Duggal, H; Bagul, KT; Kamble, S; Lokhande, P; Gacche, R; Meshram, R in [Patil, Avinash; Duggal, Harleen; Bagul, Kamini T.; Lokhande, Pradeep; Meshram, Rohan] Savitribai Phule Pune Univ, Dept Chem, Pune, Maharashtra, India; [Duggal, Harleen; Bagul, Kamini T.; Meshram, Rohan] Savitribai Phule Pune Univ, Bioinformat Ctr, Dept Biotechnol, Pune, Maharashtra, India; [Kamble, Sonali] Gramin Sci Vocat Coll, Vishnupuri, Nanded, India; [Gacche, Rajesh] Savitribai Phule Pune Univ, Dept Biotechnol, Pune, Maharashtra, India published Synthesis of New 3-Arylaminophthalides and 3-Indolyl-phthalides using Ammonium Chloride, Evaluation of their Anti-Mycobacterial Potential and Docking Study in 2020, Cited 73. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2.

Objective: The study aims at the derivatization of Phthalides and synthesizes 3-arylaminophthalides & 3-indolyl-phthalides compounds, and evaluates their anti-tubercular and antioxidant activities. The study has also intended to employ the in silica methods for the identification of possible drug targets in Mycobacterium and evaluate the binding affinities of synthesized compounds. Methods: This report briefly explains the synthesis of phthalide derivatives using ammonium chloride. The synthesized compounds were characterized using spectral analysis. Resazurin Microtiter Assay (REMA) plate method was used to demonstrate the anti-mycobacterial activity of the synthesized compounds. An in-silico pharmacophore probing approach was used for target identification in Mycobacterium. The structural level interaction between the identified putative drug target and synthesized phthalides was studied using Lamarckian genetic algorithm-based software. Results and Discussion: In the present study, we report an effective, environmentally benign scheme for the synthesis of phthalide derivatives. Compounds 5c and 5d from the current series appear to possess good anti-mycobacterial activity. dCTP: deaminasedUTPase was identified as a putative drug target in Mycobacterium. The docking results clearly showed the interactive involvement of conserved residues of dCTP with the synthesized phthalide compounds. Conclusion: On the eve of evolving anti-TB drug resistance, the data on anti-tubercular and allied activities of the compounds in the present study demonstrates the enormous significance of these newly synthesized derivatives as possible candidate leads in the development of novel anti-tubercular agents. The docking results from the current report provide a structural rationale for the promising anti-tubercular activity demonstrated by 3-arylaminophthalides and 3-indolyl-phthalides compounds.

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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem

In 2020 LIFE SCI published article about 2-AMINOTHIAZOLE DERIVATIVES; ANTIVIRAL ACTIVITY; ALPHA; POTENT; DISCOVERY; ADIPOGENESIS; METABOLISM; BENZAMIDES; INDOLES; ACID in [Mourad, Ahmed A. E.] Port Said Univ, Fac Pharm, Pharmacol & Toxicol Dept, Port Said, Egypt; [Mourad, Mai A. E.] Port Said Univ, Fac Pharm, Med Chem Dept, Port Said, Egypt in 2020, Cited 42. The Name is Isobenzofuran-1(3H)-one. Through research, I have a further understanding and discovery of 87-41-2. Computed Properties of C8H6O2

Aims: Partial PPAR gamma agonists attracted substantially heightened interest as safer thiazolidinediones alternatives. On the other hand, Wnt/beta-catenin antagonists have been highlighted as promising strategy for type 2 diabetes management via up-regulating PPAR gamma gene expression. We aimed at synthesizing novel partial PPAR gamma agonists with beta-catenin inhibitory activity which could enhance insulin sensitivity and avoid the side effects of full PPAR gamma agonists. Main methods: We synthesized novel series of alpha-phthlimido-o-toluoyl-2-aminothiazoles hybrids for evaluating their antidiabetic activity and discovering its mechanistic pathway. We assessed effect of the new hybrids on PPAR gamma activation using a luciferase reporter assay system. Moreover, intracellular triglyceride levels, gene levels of c/EBP alpha, PPAR gamma and PPAR gamma targets including GLUT4, adiponectin, aP2 were measured in 3T3-L1 cells. Uptake of 2-DOG together with PPAR gamma and beta-catenin protein levels were evaluated in 3T3-L1cells. In addition, molecular docking studies with PPAR gamma LBD, physicochemical properties and structure activity relationship of the novel hybrids were also studied. Key findings: Three of the synthesized hybrids showed partial PPAR gamma agonistic activity and distinct PPAR gamma binding pattern. These compounds modulated PPAR gamma gene expression and PPAR gamma target genes; and increased glucose uptake in 3T3-L1 and slightly induced adipogenesis compared to rosiglitazone. Moreover, these compounds reduced beta-catenin protein level which reflected in increased both PPAR gamma gene and protein levels that leads to improved insulin sensitivity and increased GLUT4 and adiponectin gene expression. Significance: Our synthesized compounds act as novel partial PPAR gamma agonists and beta-catenin inhibitors that have potent insulin sensitizing activity and mitigate the lipogenic side effects of TZDs.

Computed Properties of C8H6O2. Bye, fridends, I hope you can learn more about C8H6O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem