Luminescent metal organic frameworks-based chemiluminescence resonance energy transfer platform for turn-on detection of fluoride ion was written by Sun, Yuan;Xu, Xiaotong;Zhao, Yaxin;Tan, Haonan;Li, Yinhuan;Du, Jianxiu. And the article was included in Talanta in 2020.Safety of 2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one This article mentions the following:
A luminescent metal organic frameworks (MOFs)-based chemiluminescence resonance energy transfer (CRET) platform was constructed for turn-on detection of fluoride ion. A hybrid MOFs was prepared by encapsulating strong fluorescence 2′,7′-dichlorofluorescein (DCF) into the frames of NH2-MIL-101(Al) MOFs, which led to a significant suppression of fluorescence signal of DCF. In the presence of fluoride ion, it destroyed the structure of the hybrid MOFs and released DCF mols. from the frames due to the formation of more stable aluminum hexafluoride complex ions [AlF3-6] between fluoride ion and aluminum ion. The released DCF mols. accepted the energy originating from the chem. reaction of bis(2,4,6-trichlorophenyl)oxalate (TCPO) with hydrogen peroxide (H2O2), producing a strong chemiluminescence (CL) emission. The CL signal was strong dependent on the concentration of fluoride ion presented and showed a linear response in the range of 0.5-80.0μmol L-1 (9.5μg L-1-1.52 mg L-1). The detection limit was 0.05μmol L-1 (about 0.95μg L-1) fluoride ion and the relative standard deviations was 2.3% for 40.0μmol L-1 fluoride ion solution (n = 11). This MOFs-based CRET method was successfully applied to the determination of fluoride ion in drinking water samples, demonstrating its potential application in anal. of real samples. In the experiment, the researchers used many compounds, for example, 2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0Safety of 2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one).
2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one (cas: 76-54-0) belongs to benzofurans derivatives. Benzofuran is a core structural unit found in many naturally occurring compounds with multidirectional biological activities. Benzofurans are stable towards alkali and readily polymerize on treatment with sulfuric acid, due to which they are useful for the preparation of low cost chemically relatively inert resins.Safety of 2′,7′-Dichloro-3′,6′-dihydroxy-3H-spiro[isobenzofuran-1,9′-xanthen]-3-one
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem