Direct carboxylation of simple arenes with CO2 through a rhodium-catalyzed C-H bond activation was written by Suga, Takuya;Mizuno, Hajime;Takaya, Jun;Iwasawa, Nobuharu. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2014.Electric Literature of C10H8O3 This article mentions the following:
Direct carboxylation of simple arenes under atm. pressure of CO2 is achieved through a rhodium-catalyzed C-H bond activation without the assistance of a directing group. Various arenes such as benzene, toluene, xylene, electron-rich or electron-deficient benzene derivatives, and heteroaromatics are directly carboxylated with high TONs. In the experiment, the researchers used many compounds, for example, Methyl benzofuran-2-carboxylate (cas: 1646-27-1Electric Literature of C10H8O3).
Methyl benzofuran-2-carboxylate (cas: 1646-27-1) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Benzofurans have also made significant and distinctive contributions to biology. They exhibit several biological activities that range from antioxidant, antitubercular, antiplasmodial, insecticidal.Electric Literature of C10H8O3
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem