On September 25, 2014, Smith, Nicholas D.; Govek, Steven P.; Kahraman, Mehmet; Bonnefous, Celine; Julien, Jackaline D. published a patent.Name: 5-Iodobenzofuran The title of the patent was Polycyclic estrogen receptor modulators and uses thereof. And the patent contained the following:
The invention relates to estrogen receptor modulators (e.g., I) and their pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical preparations comprising them, and their use in the treatment of diseases or conditions that are mediated or dependent upon estrogen receptors. For instance, the invention compound I was prepared and gave a MCF7 inhibition IC50 value of ≤100nM in breast cancer cell ER-α in cell western assay. The experimental process involved the reaction of 5-Iodobenzofuran(cas: 60770-67-4).Name: 5-Iodobenzofuran
The Article related to estrogen receptor modulator preparation antitumor, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Name: 5-Iodobenzofuran
Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem