A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 497-23-4, Name is Furan-2(5H)-one, molecular formula is C4H4O2. In an article, author is Sivamuthuraman, Koilpitchai,once mentioned of 497-23-4, Category: benzofurans.
Catalytic enantioselective Michael addition of 2-substituted benzofuran-3-ones to 2-enoyl pyridines
An organocatalytic diastereo- and enantioselective synthesis of 2,2 ‘-disubstituted benzofuran-3-ones bearing adjacent quaternary and tertiary stereocenters has been achieved through Michael addition of 2-substituted benzofuran-3-ones to 2-enoyl pyridines. Both the enantiomeric forms of the major diastereomer were obtained using l-proline derived squaramide and quinine derived bis squaramide with excellent yield (up to 98%) and stereoselectivities (up to 97 : 3 dr and 98% ee). The control experiment revealed that the presence and position of nitrogen atoms in the 2-enoylpyridine have played a crucial role in the stereochemical outcome of the product.
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Reference:
Benzofuran – Wikipedia,
,Benzofuran | C8H6O – PubChem