Nguyen, Thi Thanh Binh published the artcileSynthesis and biological evaluation of novel heterocyclic derivatives of combretastatin A-4, Category: benzofurans, the publication is Bioorganic & Medicinal Chemistry Letters (2012), 22(23), 7227-7231, database is CAplus and MEDLINE.
A novel series of combretastatin A-4 heterocyclic analogs was prepared by replacement of the B ring with indole, benzofuran or benzothiophene, attached at the C2 position. These compounds were evaluated for their abilities to inhibit tubulin assembly: derivative cis-I, having a benzothiophene, showed an activity similar to those of colchicine or deoxypodophyllotoxin. The antiproliferative and antimitotic properties of cis-I against keratinocyte cancer cell lines were also evaluated and the intracellular organization of microtubules in the cells after treatment with both stereoisomers of I was also determined, using confocal microscopy.
Bioorganic & Medicinal Chemistry Letters published new progress about 69626-75-1. 69626-75-1 belongs to benzofurans, auxiliary class Iodide,Benzofuran, name is 2-Iodobenzofuran, and the molecular formula is C8H5IO, Category: benzofurans.
Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem