Nassra, Merian published the artcileInhibitory activity of plant stilbenoids against nitric oxide production by lipopolysaccharide-activated microglia, Category: benzofurans, the publication is Planta Medica (2013), 79(11), 966-970, database is CAplus and MEDLINE.
Microglia-driven inflammatory processes are thought to play an important role in ageing and several neurol. disorders. Since consumption of a diet rich in polyphenols has been associated with anti-inflammatory and neuroprotective effects, we studied the effects of twenty-five stilbenoids isolated from Milicia excelsa, Morus alba, Gnetum africanum, and Vitis vinifera. These compounds were tested at 5 and 10 μM on BV-2 microglial cells stimulated with bacterial lipopolysaccharide. Ten stilbenoids reduced lipopolysaccharide-induced nitric oxide production at 5 and/or 10 μM. Two tetramers, E-vitisin A and E-vitisin B, were the most effective mols. Moreover, they attenuated the expression of the inducible NO synthase protein and gene.
Planta Medica published new progress about 56317-21-6. 56317-21-6 belongs to benzofurans, auxiliary class Metabolic Enzyme,PDE,Natural product, name is 5-(6-Hydroxybenzofuran-2-yl)benzene-1,3-diol, and the molecular formula is C14H10O4, Category: benzofurans.
Referemce:
https://en.wikipedia.org/wiki/Benzofuran,
Benzofuran | C8H6O – PubChem