Kadzinski, Leszek et al. published their research in LWT–Food Science and Technology in 2018 | CAS: 38183-12-9

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Formula: C17H10O4

Determination of ten sulfonamides in honey using tetrahydrofuran Salting Out Liquid Liquid Extraction and monolithic silica column was written by Kadzinski, Leszek;Banasiuk, Rafal;Banecki, Bogdan. And the article was included in LWT–Food Science and Technology in 2018.Formula: C17H10O4 This article mentions the following:

This study presented a novel extraction method using acid hydrolysis and salting out liquid-liquid extraction (SALLE) using THF without the need of the cleanup or sample evaporation step, and a simple HPLC-fluorescence method with pre-column derivatization using a reverse phase C18 monolith column for detection of 10 sulfonamides in honey. Different sulfonamides such as sulfathiazole, sulfamethazine, sulfamerazine, sulfanilamide, sulfamethoxypyridazine, sulfachloropyridazine, sulfacetamide, sulfamethoxazole, sulfadimethoxine and sulfadiazine were extracted from wildflower honey samples by salting out liquid-liquid extraction with THF. Stability of derivatized sulfonamide samples were detected in different solvents like THF, methanol and citrate buffer pH 3.5. HPLC-fluorescence method developed using monolithic silica column demonstrated to be specific, because no interfering peaks were observed at the retention time of sulfonamide analytes. The author concluded that the SALLE extraction and HPLC-fluorescence method developed in this study was specific, accurate and precise over a linear dynamic range for detecting sulfonamides in honey samples. In the experiment, the researchers used many compounds, for example, 4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9Formula: C17H10O4).

4-Phenyl-3H,3’H-spiro[furan-2,1′-isobenzofuran]-3,3′-dione (cas: 38183-12-9) belongs to benzofurans derivatives. Benzofuran derivatives are one of the most important oxygen-containing heterocycles. Substituted benzofurans find applications such as fluorescent sensors, oxidants, in drug discovery, and in another field of chemistry and agriculture.Formula: C17H10O4

Referemce:
Benzofuran – Wikipedia,
Benzofuran | C8H6O – PubChem